ReviewCurrent opinion in psychiatry2011
Response to treatment in bipolar disorder.
Review in Current opinion in psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gene expression meta-analysis in the prefrontal cortex: unraveling biological underpinnings of suicidal risk.BMC psychiatry · 2026Pooled it
- Genetic predictors of lithium response in an ethiopian cohort of patients with bipolar disorder.Annals of general psychiatry · 2026Article
- Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder.Translational psychiatry · 2021Article
- The Genetics of Response to and Side Effects of Lithium Treatment in Bipolar Disorder: Future Research Perspectives.Frontiers in pharmacology · 2021Review
- Medical Comorbidities in 181 Patients With Bipolar DisorderFrontiers in psychiatry · 2021Article
- International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic).European archives of psychiatry and clinical neuroscience · 2020Article
- Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.Molecular psychiatry · 2018Article
- Omics-Based Biomarkers: Application of Metabolomics in Neuropsychiatric Disorders.The international journal of neuropsychopharmacology · 2015Review
- CRY1 Variations Impacts on the Depressive Relapse Rate in a Sample of Bipolar Patients.Psychiatry investigation · 2015Article
- Molecular actions and clinical pharmacogenetics of lithium therapy.Pharmacology, biochemistry, and behavior · 2014Review
- Coding and noncoding gene expression biomarkers in mood disorders and schizophrenia.Disease markers · 2013Review
- Predictive animal models of mania: hits, misses and future directions.British journal of pharmacology · 2011Review
- Genes Encoding GABA-β and HT1D Receptors in Bipolar I (Manic Phase) Patients.Basic and clinical neuroscienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purpose of reviewBipolar disorder is a complex psychiatric condition that has been shown to carry a great degree of genetic loading. This review addresses current research in the genetics of treatment response in bipolar disorder, with a focus on findings that have shaped our understanding of the changing direction of this field in light of recent technological advancements. RECENT
findingsThe recent publications in bipolar disorder treatment response have helped consolidate or improve upon knowledge of susceptibility loci and genes in the field. There seems to be an increasing trend toward functionally assessing the role played by putative candidate genes and molecular factors modulating expression in bipolar disorder, as well as a movement toward more global, pathway and genome-wide-oriented research. SUMMARY: Genetic and molecular research to date in bipolar disorder treatment response has not completely answered all the lingering questions in the field, but has contributed to the development of a more patient-based understanding of treatment. In order to apply these findings at a clinical level, more comprehensive treatment response studies are imperative, combining recent advances in high-throughput genomics with functional molecular research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.