ArticleJournal of epidemiology2011
Smoking during pregnancy increases risks of various obstetric complications: a case-cohort study of the Japan Perinatal Registry Network database.
Article in Journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of Maternal Underweight on Infant and Maternal Outcomes in Japanese Women: A Systematic Review and Meta-analysis.Journal of epidemiology · 2026Pooled it
- Association Between Smoking and Hypertension in Pregnancy Among Japanese Women: A Meta-analysis of Birth Cohort Studies in the Japan Birth Cohort Consortium (JBiCC) and JECS.Journal of epidemiology · 2023Pooled it
- Partner's dual use of new tobacco products and combustible cigarettes in early pregnancy was associated with hypertensive disorders of pregnancy: a cross-sectional study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Prepregnancy body mass index and glycated albumin in the third trimester may predict infant complications in gestational diabetes mellitus: a retrospective cohort study.Diabetology international · 2023Article
- Active or passive maternal smoking increases the risk of low birth weight or preterm delivery: Benefits of cessation and tobacco control policies.Tobacco induced diseases · 2023Review
- Article
- Factors Associated with Increased Risk of Early Severe Neonatal Morbidity in Late Preterm and Early Term Infants.Journal of clinical medicine · 2021Article
- Higher prevalence of hypertensive disorders of pregnancy in women who smoke: the Japan environment and children's study.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Association between exposure to air pollution during pregnancy and false positives in fetal heart rate monitoring.Scientific reports · 2017Article
- Impact of gestational nicotine exposure on intrauterine and fetal infection in a rodent model.Biology of reproduction · 2017Article
- Epidemiology of hypertensive disorders in pregnancy: prevalence, risk factors, predictors and prognosis.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age.International journal of environmental health research · 2017Article
- Association Between Maternal Smoking During Pregnancy and Birth Weight: An Appropriately Adjusted Model From the Japan Environment and Children's Study.Journal of epidemiology · 2016Article
- The different effects of neighbourhood and individual social capital on health-compromising behaviours in women during pregnancy: a multi-level analysis.BMC public health · 2015Article
- Knowledge and attitudes of adults towards smoking in pregnancy: results from the HealthStyles© 2008 survey.Maternal and child health journal · 2015Article
- Smoking cessation in pregnancy: psychosocial interventions and patient-focused perspectives.International journal of women's health · 2015Review
- The many faces of tobacco use among women.Medical science monitor : international medical journal of experimental and clinical research · 2014Review
- Self-reported maternal cigarette smoke exposure during the periconceptional period and the risk for omphalocoele.Paediatric and perinatal epidemiology · 2014Article
- Smoking and pregnancy--a review on the first major environmental risk factor of the unborn.International journal of environmental research and public health · 2013Review
- The independent effects of second hand smoke exposure and maternal body mass index on the anthropometric measurements of the newborn.BMC public health · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe adverse effects of maternal smoking on the health of pregnant women have been examined mostly on a disease-by-disease basis. The aims of this study were to evaluate simultaneously the effects of smoking during pregnancy on various obstetric complications, using data from a large medical database, and to investigate the expediency of using a case-cohort design for such an analysis.
methodsA case-cohort study was conducted within the Japan Perinatal Registry Network database. Perinatal information on infant deliveries was entered into the database at 125 medical centers in Japan. The base population of the study was 180 855 pregnant women registered in the database from 2001 through 2005. The outcome measures were the incidences of 11 different obstetric complications. Logistic regression models were used to estimate age-adjusted risk ratios (aRRs) and relative excess incidence proportions (REIs).
resultsThe overall prevalence of smoking during pregnancy was 5.8% in the base cohort, and the prevalence was higher among younger women. A comparison of the cases and control cohort showed that smokers during pregnancy had statistically significant higher risks for preterm rupture of the membrane (aRR: 1.67, 95% confidence interval [CI]: 1.43-1.96; REI: 40.2%, 95% CI: 29.9%-49.1%), chorioamnionitis (1.65, 1.36-2.00; 39.4%, 26.4%-50.0%), incompetent cervix (1.63, 1.35-1.96; 38.5%, 25.8%-49.1%), threatened premature delivery (1.38, 1.17-1.64; 27.7%, 14.5%-38.9%), placental abruption (1.37, 1.10-1.72; 27.1%, 8.8%-41.7%), and pregnancy-induced hypertension (1.20, 1.01-1.41; 16.4%, 1.2%-29.3%).
conclusionsMaternal smoking was associated with a number of obstetric complications. This highlights the importance of smoking cessation during pregnancy. In addition, case-cohort analysis proved useful in estimating RRs for multiple outcomes in a large database.
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