SynthesisBMC medicine2010
One life ends, another begins: Management of a brain-dead pregnant mother-A systematic review-.
Synthesis in BMC medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 107 citations in OpenAlex.
- A structured analysis of the concept of brain death.Theoretical medicine and bioethics · 2026Article
- Maternal Corporeal Support in Terminal Stage Brain Astrocytoma: A Case Report and Literature Review.Healthcare (Basel, Switzerland) · 2026Article
- Polish Nursing and Midwifery Master's Students' Perceptions of Ethical and Legal Dilemmas Related to Brain Death.International journal of public health · 2025Article
- Healthy Baby Delivery After 100 Days of Somatic Support in a Brain-Dead Pregnant Woman.Case reports in obstetrics and gynecology · 2025Article
- Caring for Pregnant Patients with Cancer: A Framework for Ethical and Patient-Centred Care.Cancers · 2024Review
- Cryonics, euthanasia, and the doctrine of double effect.Philosophy, ethics, and humanities in medicine : PEHM · 2023Review
- Kidney Xenotransplantation: Are We Ready for Prime Time?Current urology reports · 2023Review
- Acute Intracranial Hypertension During Pregnancy: Special Considerations and Management Adjustments.Neurocritical care · 2022Review
- Ten Rules for the Management of Moderate and Severe Traumatic Brain Injury During Pregnancy: An Expert Viewpoint.Frontiers in neurology · 2022Review
- Brain death in early pregnancy: A legal and ethical challenge coming to your intensive care unit?Journal of the Intensive Care Society · 2021Article
- Delivery of a Healthy Baby from a Brain-Dead Woman After 117 Days of Somatic Support: A Case Report.The American journal of case reports · 2021Article
- Double Effect Donation.The Linacre quarterly · 2021Article
- South African guidelines on the determination of death.The Southern African journal of critical care : the official journal of the Critical Care Society · 2021Article
- Assessment of Somatic Support Process for Pregnant Brain Death Patients Occurring in a Transition Country Between Asia and Europe from Medical, Ethical, Legal and Religious Aspects.Journal of religion and health · 2020Article
- Controversies in Brain Death Declaration: Legal and Ethical Implications in the ICU.Current treatment options in neurology · 2020Review
- Cancer During Pregnancy: How to Handle the Bioethical Dilemmas?-A Scoping Review With Paradigmatic Cases-Based Analysis.Frontiers in oncology · 2020Article
- Organ Donation and Declaration of Death: Combined Neurologic and Cardiopulmonary Standards.The Linacre quarterly · 2019Article
- When Death Is Not the End: Continuing Somatic Care during Postmortem Pregnancy.The Linacre quarterly · 2019Article
- Brain Death and the Formation of Moral Conscience.The Linacre quarterly · 2019Article
- Vaginal delivery in the 30+4 weeks of pregnancy and organ donation after brain death in early pregnancy.BMJ case reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn accident or a catastrophic disease may occasionally lead to brain death (BD) during pregnancy. Management of brain-dead pregnant patients needs to follow special strategies to support the mother in a way that she can deliver a viable and healthy child and, whenever possible, also be an organ donor. This review discusses the management of brain-dead mothers and gives an overview of recommendations concerning the organ supporting therapy.
methodsTo obtain information on brain-dead pregnant women, we performed a systematic review of Medline, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL). The collected data included the age of the mother, the cause of brain death, maternal medical complications, gestational age at BD, duration of extended life support, gestational age at delivery, indication of delivery, neonatal outcome, organ donation of the mothers and patient and graft outcome.
resultsIn our search of the literature, we found 30 cases reported between 1982 and 2010. A nontraumatic brain injury was the cause of BD in 26 of 30 mothers. The maternal mean age at the time of BD was 26.5 years. The mean gestational age at the time of BD and the mean gestational age at delivery were 22 and 29.5 weeks, respectively. Twelve viable infants were born and survived the neonatal period.
conclusionThe management of a brain-dead pregnant woman requires a multidisciplinary team which should follow available standards, guidelines and recommendations both for a nontraumatic therapy of the fetus and for an organ-preserving treatment of the potential donor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.