ArticleBMC plant biology2010
Classification of rice (Oryza sativa L. Japonica nipponbare) immunophilins (FKBPs, CYPs) and expression patterns under water stress.
Article in BMC plant biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of identified genomic regions and candidate genes underlying salinity tolerance in rice (Oryza sativa L.).Scientific reports · 2024Pooled it
- Field-crop transcriptome models are enhanced by measurements in systematically controlled environments.Genome biology · 2025Article
- Genome-Wide Analysis of Tea FK506-Binding Proteins (FKBPs) Reveals ThatInternational journal of molecular sciences · 2025Article
- OsFKBP12 transduces the sucrose signal from OsNIN8 to the OsTOR pathway in a loosely binding manner for cell division.iScience · 2025Article
- Genome-wide identification and expression analyses ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Genome-Wide Identification and Bioinformatics Analysis of the FK506 Binding Protein Family in Rice.Genes · 2024Article
- Article
- iTRAQ-Based Quantitative Proteomics Unveils Protein Dynamics in the Root ofLife (Basel, Switzerland) · 2023Article
- Identification, characterization and spatiotemporal expression analysis of the FKBP family genes in Locusta migratoria.Scientific reports · 2023Article
- Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins fromACS infectious diseases · 2023Article
- Navigating rice seedling cold resilience: QTL mapping in two inbred line populations and the search for genes.Frontiers in plant science · 2023Article
- Genome-Wide Identification and Analysis of FKBP Gene Family in Wheat (International journal of molecular sciences · 2022Article
- The Bursaphelenchus xylophilus effector BxML1 targets the cyclophilin protein (CyP) to promote parasitism and virulence in pine.BMC plant biology · 2022Article
- Genome-wide characterization and identification of cyclophilin genes associated with leaf rust resistance in bread wheat (Frontiers in genetics · 2022Article
- Cyclophilins and Their Functions in Abiotic Stress and Plant-Microbe Interactions.Biomolecules · 2021Review
- Genome-Wide Association Mapping of Salinity Tolerance at the Seedling Stage in a Panel of Vietnamese Landraces Reveals New Valuable QTLs for Salinity Stress Tolerance Breeding in Rice.Plants (Basel, Switzerland) · 2021Article
- Modulation of Abiotic Stress Responses in Rice by E3-Ubiquitin Ligases: A Promising Way to Develop Stress-Tolerant Crops.Frontiers in plant science · 2021Review
- Conserved Residues in the C-Terminal Domain Affect the Structure and Function of CYP38 in Arabidopsis.Frontiers in plant science · 2021Article
- Sequence characteristics of Medicago truncatula cyclophilin family members and function analysis of MsCYP20-3B involved in axillary shoot development.Molecular biology reports · 2020Article
- Plant Cyclophilins: Multifaceted Proteins With Versatile Roles.Frontiers in plant science · 2020Review
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFK506 binding proteins (FKBPs) and cyclophilins (CYPs) are abundant and ubiquitous proteins belonging to the peptidyl-prolyl cis/trans isomerase (PPIase) superfamily, which regulate much of metabolism through a chaperone or an isomerization of proline residues during protein folding. They are collectively referred to as immunophilin (IMM), being present in almost all cellular organs. In particular, a number of IMMs relate to environmental stresses.
resultsFKBP and CYP proteins in rice (Oryza sativa cv. Japonica) were identified and classified, and given the appropriate name for each IMM, considering the ortholog-relation with Arabidopsis and Chlamydomonas or molecular weight of the proteins. 29 FKBP and 27 CYP genes can putatively be identified in rice; among them, a number of genes can be putatively classified as orthologs of Arabidopsis IMMs. However, some genes were novel, did not match with those of Arabidopsis and Chlamydomonas, and several genes were paralogs by genetic duplication. Among 56 IMMs in rice, a significant number are regulated by salt and/or desiccation stress. In addition, their expression levels responding to the water-stress have been analyzed in different tissues, and some subcellular IMMs located by means of tagging with GFP protein.
conclusionLike other green photosynthetic organisms such as Arabidopsis (23 FKBPs and 29 CYPs) and Chlamydomonas (23 FKBs and 26 CYNs), rice has the highest number of IMM genes among organisms reported so far, suggesting that the numbers relate closely to photosynthesis. Classification of the putative FKBPs and CYPs in rice provides the information about their evolutional/functional significance when comparisons are drawn with the relatively well studied genera, Arabidopsis and Chlamydomonas. In addition, many of the genes upregulated by water stress offer the possibility of manipulating the stress responses in rice.
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