Evidence map›Paper›PMID 21085980›Full record

ArticleChromosoma2011

A simple and rapid method for constructing ring-X chromosomes in Drosophila melanogaster.

Mary M Golic, Kent G Golic

Abstract readEvaluation Study
In one paragraph

Article in Chromosoma, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary M GolicDepartment of Biology, University of Utah, Salt Lake City, UT 84112, USA.
Kent G Golic

Funding

Responses to Telomere LossR01GM065604 · NIGMS · UNIVERSITY OF UTAH · PI GOLIC, KENT G · 2001 to 2019
$4.9M
NIGMS NIH HHS R01 GM065604
6 · The paper itself

Abstract

Ring chromosomes are of basic interest to the geneticist and cell biologist who study their behavior in meiotic and mitotic divisions. In addition, the mitotic instability associated with some ring-X chromosomes has proven useful in Drosophila as a means to produce gynandromorphs for developmental studies. We describe a method to construct ring-X chromosomes in Drosophila via I-CreI-mediated exchange in rDNA, and then rapidly diagnose the recovery of ring chromosomes via FLP-mediated sister chromatid exchange within the ring. The method we describe provides a ready means to tailor the genetic content of ring-X chromosomes, making it suited to produce ring-X chromosomes for a variety of experimental purposes.

Indexed as

Genetic TechniquesRing ChromosomesAnimalsChromosomes, InsectDNA Restriction EnzymesDNA, RibosomalDrosophila melanogasterFemaleMaleMitosisSister Chromatid ExchangeX ChromosomeDNA Restriction EnzymesDNA, Ribosomalendodeoxyribonuclease CreI

Identifiers

PMID21085980
PMCPMC4454366

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.