Evidence map›Paper›PMID 21084460›Full record

ArticleClinical and vaccine immunology : CVI2011

The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study.

Ankie Lebon, Nelianne J Verkaik, Corné P de Vogel, Herbert Hooijkaas, Henri A Verbrugh, Willem J B van Wamel, Vincent W V Jaddoe, Albert Hofman, Peter W M Hermans, Tim J Mitchell and 2 more

Abstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. RSV enhancesInfection and immunity · 2024
    Article
  3. Article
  4. The Generation R Study: Biobank update 2015.European journal of epidemiology · 2014
    Article
  5. Panel 5: Microbiology and immunology panel.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2013
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ankie LebonThe Generation R Study Group, Erasmus Medical Center (Erasmus MC), Rotterdam, Netherlands.
Nelianne J Verkaik
Corné P de Vogel
Herbert Hooijkaas
Henri A Verbrugh
Willem J B van Wamel
Vincent W V Jaddoe
Albert Hofman
Peter W M Hermans
Tim J Mitchell
Henriette A Moll
Alex van Belkum

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colonization rates of Streptococcus pneumoniae and Staphylococcus aureus are inversely correlated in infants. Several studies have searched for determinants of this negative association. We studied the association between antipneumococcal antibodies with Staphylococcus aureus colonization and the association between antistaphylococcal antibodies with pneumococcal colonization in healthy children in the pneumococcal vaccine era. In the first year of life, no association between maternal IgG levels and colonization was seen. In addition, no association between the IgG and IgA levels in the child versus colonization status was seen.

Indexed as

Antibodies, BacterialCarrier StateCohort StudiesHumansInfantLongitudinal StudiesNasopharynxNetherlandsPneumococcal InfectionsPrevalenceStaphylococcal InfectionsStaphylococcus aureusStreptococcus pneumoniaeAntibodies, Bacterial

Identifiers

PMID21084460
PMCPMC3019791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.