Evidence map›Paper›PMID 21084064›Full record

ReviewInternational immunopharmacology2011

3G11 expression in CD4+ T cell-mediated autoimmunity and immune tolerance.

Fang Zhou, Guang-Xian Zhang, Abdolmohamad Rostami

Abstract readReview
In one paragraph

Review in International immunopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fang ZhouDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Philadelphia, PA 19107, USA.
Guang-Xian Zhang
Abdolmohamad Rostami
Thomas Jefferson University · US

Funding

TOLERENCE INDUCED BY I.V. MBP IN EAER01NS040085 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ROSTAMI, A.M. · 2000 to 2009
$2.5M
NINDS NIH HHS R01 NS040085
6 · The paper itself

Abstract

3G11 is a sialylated carbohydrate epitope of the disialoganglioside molecule expressed on mouse CD4(+) T cells. Recent research showed that 3G11 expression is related to the modulation of T cell function, i.e., 3G11(-) T cells exhibit anergic/Treg characteristics and efficiently inhibit autoimmunity in the central nervous system. The relationship between 3G11 expression and immune tolerance is summarized in this literature review.

Indexed as

Immune ToleranceAnimalsAntigens, SurfaceAutoimmunityCD4-Positive T-LymphocytesCentral Nervous SystemEpitopes, T-LymphocyteForkhead Transcription FactorsGangliosidesHumansMiceT-Lymphocytes, Regulatoryantigen 3G11, mouseAntigens, SurfaceEpitopes, T-LymphocyteForkhead Transcription FactorsFoxp3 protein, mouseGangliosidessialogangliosides

Identifiers

PMID21084064
PMCPMC3079069
OpenAlexW2057007795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.