Evidence map›Paper›PMID 21082428›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2011

eFIP: a tool for mining functional impact of phosphorylation from literature.

Cecilia N Arighi, Amy Y Siu, Catalina O Tudor, Jules A Nchoutmboube, Cathy H Wu, Vijay K Shanker

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. The eFIP system for text mining of protein interaction networks of phosphorylated proteins.Database : the journal of biological databases and curation · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cecilia N ArighiDepartment of Computer and Information Sciences, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu
Amy Y Siu
Catalina O Tudor
Jules A Nchoutmboube
Cathy H Wu
Vijay K Shanker
University of Delaware · USBiotechnology Institute · US

Funding

PRO: A Protein Ontology in Open Biomedical OntologiesR01GM080646 · NIGMS · UNIVERSITY OF DELAWARE · PI WU, CATHY H. · 2007 to 2018
$8.9M
Linking Text Mining and Data Mining for Biomedical Knowledge DiscoveryG08LM010720 · NLM · UNIVERSITY OF DELAWARE · PI WU, CATHY H. · 2010 to 2012
$438k
NIGMS NIH HHS R01 GM080646NLM NIH HHS G08 LM010720
6 · The paper itself

Abstract

Technologies and experimental strategies have improved dramatically in the field of genomics and proteomics facilitating analysis of cellular and biochemical processes, as well as of proteins networks. Based on numerous such analyses, there has been a significant increase of publications in life sciences and biomedicine. In this respect, knowledge bases are struggling to cope with the literature volume and they may not be able to capture in detail certain aspects of proteins and genes. One important aspect of proteins is their phosphorylated states and their implication in protein function and protein interacting networks. For this reason, we developed eFIP, a web-based tool, which aids scientists to find quickly abstracts mentioning phosphorylation of a given protein (including site and kinase), coupled with mentions of interactions and functional aspects of the protein. eFIP combines information provided by applications such as eGRAB, RLIMS-P, eGIFT and AIIAGMT, to rank abstracts mentioning phosphorylation, and to display the results in a highlighted and tabular format for a quick inspection. In this chapter, we present a case study of results returned by eFIP for the protein BAD, which is a key regulator of apoptosis that is posttranslationally modified by phosphorylation.

Indexed as

SoftwareAnimalsComputational BiologyData MiningHumansInternetPhosphorylationProteinsResearch ReportProteins

Identifiers

PMID21082428
PMCPMC4563866
OpenAlexW2408260152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.