Trial reportEuropean journal of applied physiology2011
Low prevalence of exercise-associated hyponatremia in male 100 km ultra-marathon runners in Switzerland.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Higher prevalence of exercise-associated hyponatremia in female than in male open-water ultra-endurance swimmers: the 'Marathon-Swim' in Lake Zurich.European journal of applied physiology · 2012Trial
- Fluid intake and changes in limb volumes in male ultra-marathoners: does fluid overload lead to peripheral oedema?European journal of applied physiology · 2012Trial
- Change in elevation predicts 100 km ultra marathon performance.Scientific reports · 2025Article
- No hyponatremia despite continuous plasma sodium decline in female runners during a seven stage ultramarathon.Scientific reports · 2025Article
- Exercise-Associated Hyponatremia: Serum Sodium, Symptomatology, Severity, and Sport Specificity.Open access journal of sports medicine · 2025Review
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 3: Heat and cold tolerance during exercise.European journal of applied physiology · 2024Review
- Thalamic Neuron Resilience during Osmotic Demyelination Syndrome (ODS) Is Revealed by Primary Cilium Outgrowth and ADP-ribosylation factor-like protein 13B Labeling in Axon Initial Segment.International journal of molecular sciences · 2023Article
- Exercise-Associated Hyponatremia in Marathon Runners.Journal of clinical medicine · 2022Review
- Exercise-Induced Hyponatremia: An Assessment of the International Hydration Recommendations Followed During the Gran Trail De Peñalara and Vitoria-Gasteiz Ironman Competitions.Frontiers in nutrition · 2021Article
- What are the Limiting Factors During an Ultra-Marathon? A Systematic Review of the Scientific Literature.Journal of human kinetics · 2020Article
- Exercise-Associated Hyponatremia in Endurance and Ultra-Endurance Performance-Aspects of Sex, Race Location, Ambient Temperature, Sports Discipline, and Length of Performance: A Narrative Review.Medicina (Kaunas, Lithuania) · 2019Review
- Physiological and Pathophysiological Responses to Ultramarathon Running in Non-elite Runners.Frontiers in physiology · 2019Article
- The prevalence of exercise-associated hyponatremia in 24-hour ultra-mountain bikers, 24-hour ultra-runners and multi-stage ultra-mountain bikers in the Czech Republic.Journal of the International Society of Sports Nutrition · 2014Article
- Swimming performances in long distance open-water events with and without wetsuit.BMC sports science, medicine & rehabilitation · 2014Article
- What do athletes drink during competitive sporting activities?Sports medicine (Auckland, N.Z.) · 2013Review
- Participation and performance trends in ultra-endurance running races under extreme conditions - 'Spartathlon' versus 'Badwater'.Extreme physiology & medicine · 2013Article
- Hyponatraemia: more than just a marker of disease severity?Nature reviews. Nephrology · 2013Review
- Substantial and reversible brain gray matter reduction but no acute brain lesions in ultramarathon runners: experience from the TransEurope-FootRace Project.BMC medicine · 2012Article
- Ad libitum fluid intake leads to no leg swelling in male Ironman triathletes - an observational field study.Journal of the International Society of Sports Nutrition · 2012Article
- No case of exercise-associated hyponatraemia in top male ultra-endurance cyclists: the 'Swiss Cycling Marathon'.European journal of applied physiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the prevalence of exercise-associated hyponatremia (EAH) in 145 male ultra-marathoners at the '100-km ultra-run' in Biel, Switzerland. Changes in body mass, urinary specific gravity, haemoglobin, haematocrit, plasma [Na(+)], and plasma volume were determined. Seven runners (4.8%) developed asymptomatic EAH. Body mass, haematocrit and haemoglobin decreased, plasma [Na(+)] remained unchanged and plasma volume increased. Δ body mass correlated with both post race plasma [Na(+)] and Δ plasma [Na(+)]. Δ plasma volume was associated with post race plasma [Na(+)]. The athletes consumed 0.65 (0.30) L/h; fluid intake correlated significantly and negatively (r = -0.50, p < 0.0001) to race time. Fluid intake was neither associated with post race plasma [Na(+)] nor with Δ plasma [Na(+)], but was related to Δ body mass. To conclude, the prevalence of EAH was low at ~5% in these male 100 km ultra-marathoners. EAH was asymptomatic and would not have been detected without the measurement of plasma [Na(+)].
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.