ArticleThe EMBO journal2010
Let's see how tmRNA rescues a stuck ribosome.
Article in The EMBO journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs.Bioorganic & medicinal chemistry · 2011Article
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Abstract
In the current issue, Weis et al (2010a) and Fu et al (2010) provide cryo-electron microscopy snapshots of different states of the bacterial ribosome-rescuing complex with tmRNA. This regulatory RNA molecule remarkably carries both tRNA- and mRNA-like elements that have to move through the ribosome machinery when it is stalled on an mRNA lacking a termination codon. The comparison of three intermediate states gives novel insights into the mechanism of tmRNA translocation and transient accommodation on the ribosome, and into trans-translation—the template switching from a defective mRNA to the short coding region of the tmRNA, which allows rescuing the stuck ribosome.
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