ArticleThe Plant cell2010
Arabidopsis β-ketoacyl-[acyl carrier protein] synthase i is crucial for fatty acid synthesis and plays a role in chloroplast division and embryo development.
Article in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.
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Who cites it
75 citing papers in PubMed, 1 synthesis or guideline pooled it, 150 citations in OpenAlex.
- Advancements in Crop PUFAs Biosynthesis and Genetic Engineering: A Systematic and Mixed Review System.International journal of molecular sciences · 2025Pooled it
- TOR Signaling as a Central Integrator of Embryogenic Reprogramming During 2,4-D-Induced Somatic Embryogenesis.International journal of molecular sciences · 2026Review
- The BnTFL1-BnJAM3-BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Integration of GWAS and WGCNA reveals novel candidate genes for cottonseed oil content in Gossypium hirsutum L.BMC plant biology · 2026Article
- Transcriptome-Based Identification ofPlants (Basel, Switzerland) · 2026Article
- Oil as a Hindrance to Oat (Foods (Basel, Switzerland) · 2026Review
- Functional diversification of WRINKLED3 integrates fatty acid metabolism with insecticidal acylsugar production in Solanaceae species.Nature communications · 2026Article
- Integrated multi-omics analysis reveals key genes and metabolic regulatory networks involved in the drought stress response of potato.Frontiers in plant science · 2026Article
- Biochemical and gene expression analyses character volatile compounds, fatty acids, and physiochemical properties ofFood chemistry: X · 2025Article
- Plastid-localized ZmENR1/ZmHAD1 complex ensures maize pollen and anther development through regulating lipid and ROS metabolism.Nature communications · 2024Article
- Genome-Wide Analysis and Characterization of theInternational journal of molecular sciences · 2024Article
- Comparative Transcriptomic and Lipidomic Analysis of Fatty Acid Accumulation in ThreeJournal of agricultural and food chemistry · 2024Article
- Overexpression of genes involved in fatty acid biosynthesis increases lipid content in the NaHCOMicrobiology spectrum · 2024Article
- Genetic diversity and candidate genes for transient waterlogging tolerance in mungbean at the germination and seedling stages.Frontiers in plant science · 2024Article
- Genetic and Morpho-Physiological Differences among Transgenic and No-Transgenic Cotton Cultivars.Plants (Basel, Switzerland) · 2023Article
- Protein interactomes for plant lipid biosynthesis and their biotechnological applications.Plant biotechnology journal · 2023Review
- Article
- A chromosome 16 deletion conferring a high sucrose phenotype in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Identification of QTLs and Putative Candidate Genes for Plant Architecture of Lotus Revealed by Regional Association Mapping.Plants (Basel, Switzerland) · 2023Article
- Phenotypic variation and quantitative trait loci for resistance to southern anthracnose and clover rot in red clover.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipid metabolism plays a pivotal role in cell structure and in multiple plant developmental processes. β-Ketoacyl-[acyl carrier protein] synthase I (KASI) catalyzes the elongation of de novo fatty acid (FA) synthesis. Here, we report the functional characterization of KASI in the regulation of chloroplast division and embryo development. Phenotypic observation of an Arabidopsis thaliana T-DNA insertion mutant, kasI, revealed multiple morphological defects, including chlorotic (in netted patches) and curly leaves, reduced fertility, and semidwarfism. There are only one to five enlarged chloroplasts in the mesophyll cells of chlorotic sectors of young kasI rosette leaves, indicating suppressed chloroplast division under KASI deficiency. KASI deficiency results in a significant change in the polar lipid composition, which causes the suppressed expression of FtsZ and Min system genes, disordered Z-ring placement in the oversized chloroplast, and inhibited polymerization of FtsZ protein at mid-site of the chloroplast in kasI. In addition, KASI deficiency results in disrupted embryo development before the globular stage and dramatically reduces FA levels (~33.6% of the wild type) in seeds. These results demonstrate that de novo FA synthesis is crucial and has pleiotropic effects on plant growth. The polar lipid supply is important for chloroplast division and development, revealing a key function of FA synthesis in plastid development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.