ArticleBMC genomics2010
Comparative physical maps derived from BAC end sequences of tilapia (Oreochromis niloticus).
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Identification and Characterization of a Non-muscular Myostatin in the Nile Tilapia.Frontiers in endocrinology · 2020Article
- Construction of a Genomic Bacterial Artificial Chromosome (BAC) Library for the Prawn Macrobrachium rosenbergii and Initial Analysis of ZW Chromosome-Derived BAC Inserts.Marine biotechnology (New York, N.Y.) · 2019Article
- A high quality assembly of the Nile Tilapia (Oreochromis niloticus) genome reveals the structure of two sex determination regions.BMC genomics · 2017Article
- miR-1338-5p Modulates Growth Hormone Secretion and Glucose Utilization by RegulatingFrontiers in physiology · 2017Article
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- A BAC based physical map and genome survey of the rice false smut fungus Villosiclava virens.BMC genomics · 2013Article
- Whole genome comparative analysis of channel catfish (Ictalurus punctatus) with four model fish species.BMC genomics · 2013Article
- Gene transfer and mutagenesis mediated by Sleeping Beauty transposon in Nile tilapia (Oreochromis niloticus).Transgenic research · 2013Article
- Comparative genomic analysis of catfish linkage group 8 reveals two homologous chromosomes in zebrafish and other teleosts with extensive inter-chromosomal rearrangements.BMC genomics · 2013Article
- Evolution of cichlid vision via trans-regulatory divergence.BMC evolutionary biology · 2012Article
- Integrating cytogenetics and genomics in comparative evolutionary studies of cichlid fish.BMC genomics · 2012Article
- A high-resolution map of the Nile tilapia genome: a resource for studying cichlids and other percomorphs.BMC genomics · 2012Article
- High throughput mining and characterization of microsatellites from common carp genome.International journal of molecular sciences · 2012Article
- Generation of the first BAC-based physical map of the common carp genome.BMC genomics · 2011Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
backgroundThe Nile tilapia is the second most important fish in aquaculture. It is an excellent laboratory model, and is closely related to the African lake cichlids famous for their rapid rates of speciation. A suite of genomic resources has been developed for this species, including genetic maps and ESTs. Here we analyze BAC end-sequences to develop comparative physical maps, and estimate the number of genome rearrangements, between tilapia and other model fish species.
resultsWe obtained sequence from one or both ends of 106,259 tilapia BACs. BLAST analysis against the genome assemblies of stickleback, medaka and pufferfish allowed identification of homologies for approximately 25,000 BACs for each species. We calculate that rearrangement breakpoints between tilapia and these species occur about every 3 Mb across the genome. Analysis of 35,000 clones previously assembled into contigs by restriction fingerprints allowed identification of longer-range syntenies.
conclusionsOur data suggest that chromosomal evolution in recent teleosts is dominated by alternate loss of gene duplicates, and by intra-chromosomal rearrangements (~one per million years). These physical maps are a useful resource for comparative positional cloning of traits in cichlid fishes. The paired BAC end sequences from these clones will be an important resource for scaffolding forthcoming shotgun sequence assemblies of the tilapia genome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.