Evidence map›Paper›PMID 21079631›Full record

ReviewNature immunology2010

More things in heaven and earth: defining innate and adaptive immunity.

Christine A Biron

Abstract readCommentReview
PubMed Publisher
In one paragraph

Review in Nature immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Activating natural killer (NK) cytotoxicity of canine CD5Iranian journal of veterinary research · 2018
    Article
  2. Review
  3. Article
  4. Article
  5. Memory NK cells: why do they reside in the liver?Cellular & molecular immunology · 2013
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Christine A BironDepartment of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA. christine_biron@brown.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer cells have emerged as key components of innate immunity with critical antimicrobial functions. New work showing that they can also be accessed by vaccination to deliver antigen-specific memory responses and protect against subsequent viral infections challenges the traditional distinctions made between innate and adaptive immunity.

Indexed as

Adaptive ImmunityAnimalsHumansImmunity, InnateImmunologic MemoryKiller Cells, NaturalVaccination

Identifiers

PMID21079631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.