ArticleProceedings of the National Academy of Sciences of the United States of America2010
Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers, 1 of them a synthesis that pooled it.
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Who cites it
163 citing papers in PubMed, 1 synthesis or guideline pooled it, 304 citations in OpenAlex.
- A genome-wide association study identifies variants underlying the Arabidopsis thaliana shade avoidance response.PLoS genetics · 2012Pooled it
- Highly Polygenic Control of Photosynthetic Responses to Nighttime Temperature Studied by Genomic Prediction.Plant, cell & environment · 2026Article
- Natural variation links seedling hypocotyl growth with water loss in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Does genetic variation in controlled experiments predict phenology of wild plants?Journal of evolutionary biology · 2026Article
- Genome-wide association analysis to identify QTLs and candidate genes associated with grain yield and its related traits under low light conditions in rice (Oryza sativa L.).The plant genome · 2026Article
- Does genetic variation in controlled experiments predict phenology of wild plants?bioRxiv : the preprint server for biology · 2025Article
- Species-wide gene editing of a flowering regulator reveals hidden phenotypic variation.PLoS biology · 2025Article
- Beyond the Standard GWAS-A Guide for Plant Biologists.Plant & cell physiology · 2025Review
- Natural expression variation for the ArabidopsisFrontiers in plant science · 2025Article
- The benefits of permutation-based genome-wide association studies.Journal of experimental botany · 2024Article
- The natural variance of Arabidopsis secondary metabolism on extended darkness.Scientific data · 2024Article
- Landscape genomics reveals genetic signals of environmental adaptation of African wild eggplants.Ecology and evolution · 2024Article
- Dual-trait genomic analysis in highly stratified Arabidopsis thaliana populations using genome-wide association summary statistics.Heredity · 2024Article
- Flowering time: From physiology, through genetics to mechanism.Plant physiology · 2024Review
- Genome-wide association analysis reveals genes controlling an antagonistic effect of biotic and osmotic stress on Arabidopsis thaliana growth.Molecular plant pathology · 2024Article
- Genome-wide association studies identify loci controlling specialized seed metabolites in Arabidopsis.Plant physiology · 2024Article
- Genetic adaptations in the population history of Arabidopsis thaliana.G3 (Bethesda, Md.) · 2023Article
- Genome-wide association study unveils ascorbate regulation by PAS/LOV PROTEIN during high light acclimation.Plant physiology · 2023Article
- Genetic Architecture of Flowering Time Differs Between Populations With Contrasting Demographic and Selective Histories.Molecular biology and evolution · 2023Article
- Screening and validation of salt-stress responsive cg-SSR markers in wheat (Triticum aestivum L.) germplasm of Pakistan.Molecular biology reports · 2023Article
103 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Flowering time (FT) is the developmental transition coupling an internal genetic program with external local and seasonal climate cues. The genetic loci sensitive to predictable environmental signals underlie local adaptation. We dissected natural variation in FT across a new global diversity set of 473 unique accessions, with >12,000 plants across two seasonal plantings in each of two simulated local climates, Spain and Sweden. Genome-wide association mapping was carried out with 213,497 SNPs. A total of 12 FT candidate quantitative trait loci (QTL) were fine-mapped in two independent studies, including 4 located within ±10 kb of previously cloned FT alleles and 8 novel loci. All QTL show sensitivity to planting season and/or simulated location in a multi-QTL mixed model. Alleles at four QTL were significantly correlated with latitude of origin, implying past selection for faster flowering in southern locations. Finally, maximum seed yield was observed at an optimal FT unique to each season and location, with four FT QTL directly controlling yield. Our results suggest that these major, environmentally sensitive FT QTL play an important role in spatial and temporal adaptation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.