ArticleAntimicrobial agents and chemotherapy2011
rmtD2, a new allele of a 16S rRNA methylase gene, has been present in Enterobacteriaceae isolates from Argentina for more than a decade.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Changing landscape of 16 S-RMTase-mediated aminoglycoside resistance in clinical Klebsiella pneumoniae isolates from Chile between 1997 and 2023.Scientific reports · 2026Article
- First Report in the Americas ofAntibiotics (Basel, Switzerland) · 2025Article
- First Detection of High-Level Aminoglycoside-ResistantAntibiotics (Basel, Switzerland) · 2024Article
- Emergence of NDM-producing Enterobacterales infections in companion animals from Argentina.BMC veterinary research · 2024Article
- Research Updates of Plasmid-Mediated Aminoglycoside Resistance 16S rRNA Methyltransferase.Antibiotics (Basel, Switzerland) · 2022Review
- 16S rRNA Methyltransferases as Novel Drug Targets Against Tuberculosis.The protein journal · 2022Review
- A New Variant of 16S rRNA Methylase, RmtD3, in a Clinical Isolate of Pseudomonas aeruginosa in Myanmar.Antimicrobial agents and chemotherapy · 2018Article
- Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases.Infectious disease clinics of North America · 2016Review
- Complete Sequences of Multidrug Resistance Plasmids Bearing rmtD1 and rmtD2 16S rRNA Methyltransferase Genes.Antimicrobial agents and chemotherapy · 2016Article
- Mechanisms of Resistance to Aminoglycoside Antibiotics: Overview and Perspectives.MedChemComm · 2016Article
- Heterologous Expression and Functional Characterization of the Exogenously Acquired Aminoglycoside Resistance Methyltransferases RmtD, RmtD2, and RmtG.Antimicrobial agents and chemotherapy · 2016Article
- Complete sequence of conjugative IncA/C plasmid encoding CMY-2 β-lactamase and RmtE 16S rRNA methyltransferase.Antimicrobial agents and chemotherapy · 2015Article
- Identification of aminoglycoside-resistant Pseudomonas aeruginosa producing RmtG 16S rRNA methyltransferase in a cystic fibrosis patient.Antimicrobial agents and chemotherapy · 2015Article
- Characterization of multiple NDM-1-producing Enterobacteriaceae isolates from the same patient.Antimicrobial agents and chemotherapy · 2015Article
- Molecular characterization of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae in Ontario, Canada, 2008-2011.PloS one · 2014Article
- Differential distribution of plasmid-mediated quinolone resistance genes in clinical enterobacteria with unusual phenotypes of quinolone susceptibility from Argentina.Antimicrobial agents and chemotherapy · 2013Article
- Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum β-lactamases in Klebsiella pneumoniae.Antimicrobial agents and chemotherapy · 2013Article
- RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family.Antimicrobial agents and chemotherapy · 2012Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
The first allele of a 16S rRNA methyltransferase gene, rmtD2, conferring very high resistance to all clinically available aminoglycosides, was detected in 7/1,064 enterobacteria collected in 2007. rmtD2 was located on a conjugative plasmid in a Tn2670-like element inside a structure similar to that of rmtD1 but probably having an independent assembly. rmtD2 has been found since 1996 to 1998 mainly in Enterobacter and Citrobacter isolates, suggesting a possible reservoir in these genera. This presumption deserves monitoring by continuous surveillance.
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