Evidence map›Paper›PMID 21078454›Full record

ReviewClinics in perinatology2010

Survival and health benefits of breastfeeding versus artificial feeding in infants of HIV-infected women: developing versus developed world.

Louise Kuhn, Grace Aldrovandi

Abstract readComparative StudyReview
In one paragraph

Review in Clinics in perinatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Louise KuhnGertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA. lk24@columbia.edu
Grace Aldrovandi

Funding

LC - IMPAACT Leadership GroupUM1AI106716 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$47.2M
Short Exclusive Breastfeeding to Reduce Postnatal Transmission of HIVR01HD039611 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI THEA, DONALD M · 2000 to 2006
$8.0M
Pathogenesis of Mother to Child Transmission of HIVR01HD040777 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALDROVANDI, GRACE M · 2002 to 2011
$4.4M
Safer Weaning Practices for HIV-infected womenR01HD057617 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KUHN, LOUISE · 2007 to 2011
$2.0M
Oral Transmission of HIV through BreastfeedingR01DE021238 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALDROVANDI, GRACE M, KUHN, LOUISE · 2010 to 2013
$1.7M
NIAID NIH HHS UM1 AI106716NICHD NIH HHS HD 39611NICHD NIH HHS HD 40777NICHD NIH HHS HD 57161NICHD NIH HHS R01 HD039611NICHD NIH HHS R01 HD040777NICHD NIH HHS R01 HD057617NIDCR NIH HHS R01 DE021238
6 · The paper itself

Abstract

Infant feeding policies for HIV-infected women in developing countries differ from policies in developed countries. This article summarizes the epidemiologic data on the risks and benefits of various infant feeding practices for HIV-infected women living in different contexts. Artificial feeding can prevent a large proportion of mother-to-child HIV transmission but also is associated with increases in morbidity and mortality among exposed-uninfected and HIV-infected children. Antiretroviral drugs can be used during lactation and reduce risks of transmission. For most of the developing world, the health and survival benefits of breastfeeding exceed the risks of HIV transmission, especially when antiretroviral interventions are provided.

Indexed as

Bottle FeedingBreast FeedingDeveloped CountriesDeveloping CountriesInfant WelfareFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalSurvival Rate

Identifiers

PMID21078454
PMCPMC3008406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.