Evidence map›Paper›PMID 21078447›Full record

ArticleClinics in perinatology2010

Viral sequence analysis from HIV-infected mothers and infants: molecular evolution, diversity, and risk factors for mother-to-child transmission.

Philip L Bulterys, Sudeb C Dalai, David A Katzenstein

Open access · greenAbstract read
In one paragraph

Article in Clinics in perinatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Philip L BulterysDepartment of Biology, Stanford University, 371 Serra Mall, Stanford, CA 94305-4200, USA.
Sudeb C Dalai
David A Katzenstein
Stanford University · USUniversity of California, Berkeley · USUniversity of California, Los Angeles · US

Funding

African Program for Research training in HIV, TB and associated opportunistic infU2RTW006878 · FIC · STANFORD UNIVERSITY · PI KATZENSTEIN, DAVID ALLENBERG · 2005 to 2009
$747k
FIC NIH HHS U2R TW006878Howard Hughes Medical Institute
6 · The paper itself

Abstract

Great progress has been made in understanding the pathogenesis, treatment, and transmission of HIV and the factors influencing the risk of mother-to-child transmission (MTCT). Many questions regarding the molecular evolution and genetic diversity of HIV in the context of MTCT remain unanswered. Further research to identify the selective factors governing which variants are transmitted, how the compartmentalization of HIV in different cells and tissues contributes to transmission, and the influence of host immunity, viral diversity, and recombination on MTCT may provide insight into new prevention strategies and the development of an effective HIV vaccine.

Indexed as

Evolution, MolecularGenetic VariationInfectious Disease Transmission, VerticalAnti-Retroviral AgentsCancer VaccinesDrug DesignDrug Resistance, ViralFemaleHIVHIV InfectionsHumansInfant, NewbornPregnancyPregnancy Complications, InfectiousRecombination, GeneticRisk FactorsAnti-Retroviral AgentsCancer Vaccines

Identifiers

PMID21078447
PMCPMC3175486
OpenAlexW1965563114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.