ReviewBiology of the cell2010
How ubiquitination and autophagy participate in the regulation of the cell response to bacterial infection.
Review in Biology of the cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed.
- Autophagy and Bacterial infections.Autophagy reports · 2025Review
- Host SUMOylation in bacterial infections and immune defense mechanisms.Frontiers in microbiology · 2025Review
- Differential gene expression of Asian citrus psyllids infected with 'Frontiers in plant science · 2023Article
- Roles of Autophagy in Oxidative Stress.International journal of molecular sciences · 2020Review
- Transcriptome Analyses of Diaphorina citri Midgut Responses to Candidatus Liberibacter Asiaticus Infection.Insects · 2020Article
- p62/SQSTM1 promotes rapid ubiquitin conjugation to target proteins after endosome rupture during xenophagy.FEBS open bio · 2018Article
- Alterations of theFrontiers in cellular and infection microbiology · 2017Article
- The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?Immunological reviews · 2015Review
- Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged with Staphylococcus epidermidis.Journal of cellular and molecular medicine · 2015Article
- Cell death and autophagy in tuberculosis.Seminars in immunology · 2014Review
- Breaking in and grabbing a meal: Anaplasma phagocytophilum cellular invasion, nutrient acquisition, and promising tools for their study.Microbes and infection · 2013Review
- Sterical hindrance promotes selectivity of the autophagy cargo receptor NDP52 for the danger receptor galectin-8 in antibacterial autophagy.Science signaling · 2013Article
- Pathogen-induced autophagy signaling in innate immunity.Journal of innate immunity · 2013Review
- The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole.Biology open · 2012Article
- Autophagy modulation as a potential therapeutic target for diverse diseases.Nature reviews. Drug discovery · 2012Review
- Autophagy in immunity: implications in etiology of autoimmune/autoinflammatory diseases.Autophagy · 2012Review
- The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates.PLoS pathogens · 2012Article
- Ubiquitin and ubiquitin-modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU.Molecular microbiology · 2011Article
- New thoughts regarding Atg8 and ubiquitination.Autophagy · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial infection relies on the micro-organism's ability to orchestrate the host's cell signalling such that the immune response is not activated. Conversely, the host cell has dedicated signalling pathways for coping with intrusions by pathogens. The autophagy of foreign micro-organisms (known as xenophagy) has emerged as one of the most powerful of these pathways, although the triggering mode remains largely unknown. In the present paper, we discuss the role that certain post-translational modifications (primarily ubiquitination) may play in the activation of xenophagy and how some bacteria have evolved mechanisms to subvert or hijack this process. In particular, we address the role played by P62/SQSTM1 (sequestosome 1). Finally, we discuss how autophagy can be subverted to eliminate bacteria-induced danger signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.