ArticleCancer investigation2010
Obesity and microvascular invasion in hepatocellular carcinoma.
Article in Cancer investigation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Chinese expert consensus on the diagnosis and treatment of hepatocellular carcinoma with microvascular invasion (2024 edition).Hepatobiliary surgery and nutrition · 2025Review
- Obesity and cancer-extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases.Cancer metastasis reviews · 2022Review
- [Research progress of microvascular invasion in hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Review
- [The consensus on tertiary prevention of primary liver cancer (2022 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- Preoperative Assessment of Abdominal Adipose Tissue to Predict Microvascular Invasion in Small Hepatocellular Carcinoma.Journal of clinical and translational hepatology · 2022Article
- A Radiomics Model Based on Gd-EOB-DTPA-Enhanced MRI for the Prediction of Microvascular Invasion in Solitary Hepatocellular Carcinoma ≤ 5 cm.Frontiers in oncology · 2022Article
- Preoperative prediction of early recurrence of HBV-related hepatocellular carcinoma (≤5 cm) by visceral adipose tissue index.Frontiers in surgery · 2022Article
- New insights into a microvascular invasion prediction model in hepatocellular carcinoma: A retrospective study from the SEER database and China.Frontiers in surgery · 2022Article
- Prediction of Microvascular Invasion and Its M2 Classification in Hepatocellular Carcinoma Based on Nomogram Analyses.Frontiers in oncology · 2021Article
- A Nomogram for Preoperative Estimation of Microvascular Invasion Risk in Hepatocellular Carcinoma: Single-Center Analyses With Internal Validation.Frontiers in oncology · 2021Article
- Obesity and Energy Balance in GI Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016Review
- Obesity and Cancer: An Angiogenic and Inflammatory Link.Microcirculation (New York, N.Y. : 1994) · 2016Review
- Obesity Early in Adulthood Increases Risk but Does Not Affect Outcomes of Hepatocellular Carcinoma.Gastroenterology · 2015Article
- Serum adiponectin is associated with worsened overall survival in a prospective cohort of hepatocellular carcinoma patients.Oncology · 2015Article
- Diabetes, body mass index, and outcomes in hepatocellular carcinoma patients undergoing liver transplantation.Transplantation · 2012Article
- Metabolic syndrome and hepatocellular carcinoma: two growing epidemics with a potential link.Cancer · 2009Review
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
Abstract
backgroundWe hypothesized that hepatocellular carcinoma (HCC) patients with higher Body Mass Index (BMI) might have more microvascular invasion (MVI) in their tumors.
methodsRecords from 138 consecutive patients who underwent surgery at Columbia University Medical Center from January 1, 2002 to January 9, 2008 were evaluated.
results40 patients (29%) had MVI, including 14% with BMI <25, 31% with BMI = 25-30, and 40% with BMI >30 (p = .05). However, only maximum alpha-fetoprotein was significantly associated with overall mortality in a Cox model.
conclusionsMVI was associated with obesity. A better understanding of the mechanism of this association may lead to interventions for the treatment and prevention of HCC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.