Evidence map›Paper›PMID 21076812›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2011

Patterns of polymorphism and linkage disequilibrium in cultivated barley.

Jordi Comadran, Luke Ramsay, Katrin MacKenzie, Patrick Hayes, Timothy J Close, Gary Muehlbauer, Nils Stein, Robbie Waugh

Abstract read
In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Breeding of Winter-Hardy Malting Barley.Plants (Basel, Switzerland) · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Evaluation of LD decay and various LD-decay estimators in simulated and SNP-array data of tetraploid potato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017
    Article
  11. Review
  12. Article
  13. Article
  14. Association mapping of salt tolerance in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013
    Article
  15. Article
  16. SNP genotyping in melons: genetic variation, population structure, and linkage disequilibrium.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013
    Article
  17. Genomics-based high-resolution mapping of the BaMMV/BaYMV resistance gene rym11 in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jordi ComadranGenetics Programme, Scottish Crop Research Institute, Dundee, Scotland, UK.
Luke Ramsay
Katrin MacKenzie
Patrick Hayes
Timothy J Close
Gary Muehlbauer
Nils Stein
Robbie Waugh

Funding

Biotechnology and Biological Sciences Research Council BB/D522003/1
6 · The paper itself

Abstract

We carried out a genome-wide analysis of polymorphism (4,596 SNP loci across 190 elite cultivated accessions) chosen to represent the available genetic variation in current elite North West European and North American barley germplasm. Population sub-structure, patterns of diversity and linkage disequilibrium varied considerably across the seven barley chromosomes. Gene-rich and rarely recombining haplotype blocks that may represent up to 60% of the physical length of barley chromosomes extended across the 'genetic centromeres'. By positioning 2,132 bi-parentally mapped SNP markers with minimum allele frequencies higher than 0.10 by association mapping, 87.3% were located to within 5 cM of their original genetic map position. We show that at this current marker density genetically diverse populations of relatively small size are sufficient to fine map simple traits, providing they are not strongly stratified within the sample, fall outside the genetic centromeres and population sub-structure is effectively controlled in the analysis. Our results have important implications for association mapping, positional cloning, physical mapping and practical plant breeding in barley and other major world cereals including wheat and rye that exhibit comparable genome and genetic features.

Indexed as

AgriculturePolymorphism, GeneticAlgorithmsChromosome MappingGenetic LinkageGenome, PlantHordeumLinkage DisequilibriumModels, GeneticPolymorphism, Single NucleotidePopulation Dynamics

Identifiers

PMID21076812
PMCPMC3026706

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.