ArticleJournal of biomedicine & biotechnology2010
High-sensitivity C-reactive protein: an independent risk factor for left ventricular hypertrophy in patients with lupus nephritis.
Article in Journal of biomedicine & biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Osteopontin associated with left ventricular hypertrophy and diastolic dysfunction in essential hypertension.Journal of human hypertension · 2020Article
- The association between BMP4 gene polymorphism and its serum level with the incidence of LVH in hypertensive patients.Journal of translational medicine · 2015Article
- Serum osteopontin, but not OPN gene polymorphism, is associated with LVH in essential hypertensive patients.Journal of molecular medicine (Berlin, Germany) · 2014Article
- Ambulatory blood pressure and subclinical cardiovascular disease in patients with juvenile-onset systemic lupus erythematosus.Pediatric nephrology (Berlin, Germany) · 2013Article
- Association of glomerular filtration rate and inflammation with left ventricular hypertrophy in chronic kidney disease patients.Hippokratia · 2012Article
- Short-term effect of fenofibrate on C-reactive protein: A meta-analysis of randomized controlled trials.Diabetology & metabolic syndrome · 2011Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the prevalence of left ventricular hypertrophy (LVH) and its associated risk factors in lupus nephritis (LN) patients.
methods287 LN patients (age: 38.54 ± 13.31, 262 female) were recruited. Echocardiography and serum high-sensitivity C-reactive protein (hs-CRP) were measured. Their relationship was evaluated by univariate correlation analysis and multivariate regression analysis.
resultsThe prevalence of LVH in this cohort was 21.25% (n = 61). Serum hs-CRP level was significantly elevated in patients with LVH compared to those without (8.03 (3.22-30.95) versus 3.93 (1.48-9.48) mg/L, P < .01), and correlated with left ventricular mass index (LVMI) (r = 0.314, P = .001). Multivariate regression analysis further confirmed that hs-CRP was an independent risk factor (β = 0.338, P = .002) for LVH in patients with LN.
conclusionsOur findings demonstrated that serum hs-CRP level is independently correlated with LVMI and suggested that measurement of hs-CRP may provide important clinical information to investigate LVH in LN patients.
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