Is shortening of telomeres the missing link between aging and the Type 2 Diabetes epidemic?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

7 citing papers in PubMed.

1. The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect?Genes · 2016
   Review
2. Shortened leukocyte telomere length in type 2 diabetes mellitus: genetic polymorphisms in mitochondrial uncoupling proteins and telomeric pathways.Clinical and translational medicine · 2016
   Article
3. Short telomere length is associated with arterial aging in patients with type 2 diabetes mellitus.Endocrine connections · 2015
   Article
4. Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging.Aging · 2012
   Article
5. Controversial aspects of oncogene-induced senescence.Cell cycle (Georgetown, Tex.) · 2012
   Review
6. Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetes.Molecular and cellular biochemistry · 2012
   Article
7. [Oxidative stress in endothelial cells and in diabetes type 2].Zeitschrift fur Gerontologie und Geriatrie · 2012
   Article

Corrections and comments

• Comment on
  Telomerase deficiency impairs glucose metabolism and insulin secretion.2010

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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