Evidence map›Paper›PMID 21076180›Full record

ArticleAging2010

Linking Klotho, Nrf2, MAP kinases and aging.

Priya Balasubramanian, Valter D Longo

Abstract readComment
In one paragraph

Article in Aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Chronic kidney disease and premature ageing.Nature reviews. Nephrology · 2014
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Priya BalasubramanianAndrus Gerontology Center, University of Southern California, Los Angeles, CA 90089, USA.
Valter D Longo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAging, PrematureAnimalsForkhead Box Protein O1Forkhead Transcription FactorsGene Expression RegulationGlucuronidaseInsulinInsulin-Like Growth Factor IKlotho ProteinsMAP Kinase Kinase Kinase 5MiceMice, KnockoutNF-E2-Related Factor 2Oxidative Stressp38 Mitogen-Activated Protein KinasesForkhead Box Protein O1Forkhead Transcription FactorsFoxo1 protein, mouseGlucuronidaseInsulinInsulin-Like Growth Factor IKlotho ProteinsMap3k5 protein, mouseMAP Kinase Kinase Kinase 5Nfe2l2 protein, mouseNF-E2-Related Factor 2p38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesSuperoxide DismutaseThioredoxins

Identifiers

PMID21076180
PMCPMC2993790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.