ReviewCarcinogenesis2011
Mutation and epigenetic molecular clocks in cancer.
Review in Carcinogenesis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Longitudinal Analyses of Mutational Subclonal Architecture and Tumor Subtypes in Recurrent Bladder Cancer.International journal of molecular sciences · 2023Article
- Inferring the Cancer Cellular Epigenome Heterogeneity via DNA Methylation Patterns.Cancer treatment and research · 2023Article
- Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.Nature genetics · 2021Article
- Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.Nature reviews. Genetics · 2021Review
- Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking.Nature communications · 2020Article
- Epigenetic Conservation Is a Beacon of Function: An Analysis Using Methcon5 Software for Studying Gene Methylation.JCO clinical cancer informatics · 2020Article
- Article
- Mutation heterogeneity between primary gastric cancers and their matched lymph node metastases.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019Article
- High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer.Nature communications · 2018Article
- Identification of a key role of widespread epigenetic drift in Barrett's esophagus and esophageal adenocarcinoma.Clinical epigenetics · 2017Article
- A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.PLoS computational biology · 2016Article
- Ultra-precise detection of mutations by droplet-based amplification of circularized DNA.BMC genomics · 2016Article
- Prognostic significance of histone methyltransferase enhancer of zeste homolog 2 in patients with cervical squamous cell carcinoma.Oncology letters · 2015Article
- BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies.Genome biology · 2015Article
- Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells.Oncotarget · 2014Article
- Advances for studying clonal evolution in cancer.Cancer letters · 2013Review
- Individual karyotypes at the origins of cervical carcinomas.Molecular cytogenetics · 2013Article
- Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization.Cancer research · 2013Article
- Cancer in light of experimental evolution.Current biology : CB · 2012Review
- Dynamics of gene duplication and transposons in microbial genomes following a sudden environmental change.Mobile genetic elements · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
A quandary of evolution is how to measure change over time. A natural inclination is to use morphologic criteria-the greater the differences between two phenotypes, the greater amount of time needed to evolve these differences. However, appearances may be deceiving, and another approach to infer time is with molecular clocks. Here, the greater the differences between two genomes, on average the greater the time since a common ancestor. Recent advances in DNA sequencing shed new light on how human cancers might evolve.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.