Evidence map›Paper›PMID 21075334›Full record

ReviewProgress in molecular biology and translational science2010

Applications of molecular imaging.

Craig J Galbán, Stefanie Galbán, Marcian E Van Dort, Gary D Luker, Mahaveer S Bhojani, Alnawaz Rehemtulla, Brian D Ross

Abstract readReview
In one paragraph

Review in Progress in molecular biology and translational science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Recent Progress in Synthesis ofNuclear medicine and molecular imaging · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Molecular imaging reveals a role for AKT in resistance to cisplatin for ovarian endometrioid adenocarcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013
    Article
  13. Article
  14. Article
  15. PET/MR in oncology: an introduction with focus on MR and future perspectives for hybrid imaging.American journal of nuclear medicine and molecular imaging · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Craig J GalbánDepartment of Radiology, University of Michigan, Center for Molecular Imaging, Ann Arbor, Michigan, USA.
Stefanie Galbán
Marcian E Van Dort
Gary D Luker
Mahaveer S Bhojani
Alnawaz Rehemtulla
Brian D Ross
University of Michigan–Ann Arbor · US

Funding

QUANTITATION OF HUMAN BRAIN TUMOR THERAPY RESPONSE BY MRP01CA085878 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROSS, BRIAN D. · 2001 to 2017
$31.9M
Small Animal Imaging CoreP50CA093990 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROSS, BRIAN D. · 2002 to 2012
$19.0M
Michigan Small Animal Imaging Resource (MSAIR)R24CA083099 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROSS, BRIAN D. · 1999 to 2006
$4.2M
NCI NIH HHS P01 CA085878NCI NIH HHS P01 CA85878NCI NIH HHS P50 CA093990NCI NIH HHS P50 CA93990NCI NIH HHS R24 CA083099NCI NIH HHS R24 CA83099
6 · The paper itself

Abstract

Today molecular imaging technologies play a central role in clinical oncology. The use of imaging techniques in early cancer detection, treatment response, and new therapy development is steadily growing and has already significantly impacted on clinical management of cancer. In this chapter, we overview three different molecular imaging technologies used for the understanding of disease biomarkers, drug development, or monitoring therapeutic outcome. They are (1) optical imaging (bioluminescence and fluorescence imaging), (2) magnetic resonance imaging (MRI), and (3) nuclear imaging (e.g., single-photon emission computed tomography (SPECT) and positron emission tomography (PET)). We review the use of molecular reporters of biological processes (e.g., apoptosis and protein kinase activity) for high-throughput drug screening and new cancer therapies, diffusion MRI as a biomarker for early treatment response and PET and SPECT radioligands in oncology.

Indexed as

AnimalsHumansMagnetic Resonance ImagingMolecular ImagingOptical DevicesRadionuclide Imaging

Identifiers

PMID21075334
PMCPMC4327770
OpenAlexW185904142

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.