ReviewThe veterinary clinics of North America. Exotic animal practice2011
Analgesia in amphibians: preclinical studies and clinical applications.
Review in The veterinary clinics of North America. Exotic animal practice, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Analysis of Gross and Histopathologic Changes from Repeated Celiotomies in African Clawed Frogs (Xenopus laevis).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Effectiveness, Safety, and Pharmacokinetics of Meloxicam Formulations in African-clawed Frogs, Xenopus laevis.Comparative medicine · 2024Article
- Comparison of Thermal and Mechanical Noxious Stimuli for Testing Analgesics in White's Tree Frogs (Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs (Journal of the American Association for Laboratory Animal Science : JAALAS · 2018Article
- Propofol (2,6-diisopropylphenol) is an applicable immersion anesthetic in the axolotl with potential uses in hemodynamic and neurophysiological experiments.Regeneration (Oxford, England) · 2017Article
- Uses and Doses of Local Anesthetics in Fish, Amphibians, and Reptiles.Journal of the American Association for Laboratory Animal Science : JAALAS · 2017Review
- Evaluation of the anesthetic effects of MS222 in the adult Mexican axolotl (Veterinary medicine (Auckland, N.Z.) · 2016Article
- Efficacy of tricaine methanesulfonate (MS-222) as an anesthetic agent for blocking sensory-motor responses in Xenopus laevis tadpoles.PloS one · 2014Article
- The Response of Gray Treefrogs to Anesthesia by Tricaine Methanesulfonate (TMS or MS-222).ISRN zoology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Preclinical studies of analgesia in amphibians or recommendations for clinical use of analgesics in amphibian species are extremely limited. This article briefly reviews the issues surrounding the use of analgesics in amphibians, starting with common definitions of pain and analgesia when applied to nonhuman animals. Nociceptive and endogenous opioid systems in amphibians are reviewed, and results of preclinical research on opioid and nonopioid analgesics summarized. Recommended opioid and nonopioid analgesics are summarized, and practical recommendations made for their clinical use.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.