ArticleVirology journal2010
Characterization of hepatitis B virus (HBV) genotypes in patients from Rondônia, Brazil.
Article in Virology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Article
- Article
- Hepatitis B in the Northwestern region of Sao Paulo State: genotypes and resistance mutations.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021Article
- Analysis of hepatitis B virus-mixed genotype infection by ultra deep pyrosequencing in Sudanese patients, 2015-2016.Infection · 2019Article
- Reconstruction of the spatial and temporal dynamics of hepatitis B virus genotype D in the Americas.PloS one · 2019Article
- In Silico Analysis of Hepatitis B Virus Occult Associated Mutations in Botswana Using a Novel Algorithm.Genes · 2018Article
- Phylogenetic analysis and genotype distribution of Hepatitis B Virus (HBV) in Roraima, Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018Article
- Sequence analysis of sub-genotype D hepatitis B surface antigens isolated from Jeddah, Saudi Arabia.Saudi journal of biological sciences · 2018Article
- Genotyping of HBV and tracking of resistance mutations in treatment-naïve patients with chronic hepatitis B.Infection and drug resistance · 2017Article
- Molecular characterisation of hepatitis B virus in HIV-1 subtype C infected patients in Botswana.BMC infectious diseases · 2015Article
- Article
- Molecular identification of hepatitis B virus genotypes/subgenotypes: revised classification hurdles and updated resolutions.World journal of gastroenterology · 2014Review
- A rare HBV subgenotype D4 with unique genomic signatures identified in north-eastern India--an emerging clinical challenge?PloS one · 2014Article
- Hepatitis B virus subgenotype A1: evolutionary relationships between Brazilian, African and Asian isolates.PloS one · 2014Article
- High diversity of hepatitis B virus genotypes in Panamanian blood donors: a molecular analysis of new variants.PloS one · 2014Article
- Epidemiology and molecular characterization of hepatitis B virus infection in isolated villages in the Western Brazilian Amazon.The American journal of tropical medicine and hygiene · 2012Article
- Article
- Detection of Hepatitis B virus subgenotype A1 in a Quilombo community from Maranhão, Brazil.Virology journal · 2011Article
- Distribution of hepatitis c virus (hcv) genotypes in patients with chronic infection from Rondônia, Brazil.Virology journal · 2011Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatitis B virus (HBV) can be classified into nine genotypes (A-I) defined by sequence divergence of more than 8% based on the complete genome. This study aims to identify the genotypic distribution of HBV in 40 HBsAg-positive patients from Rondônia, Brazil. A fragment of 1306 bp partially comprising surface and polymerase overlapping genes was amplified by PCR. Amplified DNA was purified and sequenced. Amplified DNA was purified and sequenced on an ABI PRISM® 377 Automatic Sequencer (Applied Biosystems, Foster City, CA, USA). The obtained sequences were aligned with reference sequences obtained from the GenBank using Clustal X software and then edited with Se-Al software. Phylogenetic analyses were conducted by the Markov Chain Monte Carlo (MCMC) approach using BEAST v.1.5.3.
resultsThe subgenotypes distribution was A1 (37.1%), D3 (22.8%), F2a (20.0%), D4 (17.1%) and D2 (2.8%).
conclusionsThese results for the first HBV genotypic characterization in Rondônia state are consistent with other studies in Brazil, showing the presence of several HBV genotypes that reflects the mixed origin of the population, involving descendants from Native Americans, Europeans, and Africans.
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