Evidence map›Paper›PMID 21073313›Full record

ReviewFuture microbiology2010

The Streptococcus pyogenes proteome: maps, virulence factors and vaccine candidates.

Alexander V Dmitriev, Michael S Chaussee

Open access · greenAbstract readReview
In one paragraph

Review in Future microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Biological Characterization and Inhibition ofMolecules (Basel, Switzerland) · 2019
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Postpartum group a Streptococcus sepsis and maternal immunology.American journal of reproductive immunology (New York, N.Y. : 1989) · 2012
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander V DmitrievDepartment of Molecular Microbiology, Institute of Experimental Medicine. acad. Pavlov str., 12, Saint-Petersburg, 197376, Russia.
Michael S Chaussee
Institute of Experimental Medicine · RU

Funding

Wichozani-A Healthy Lifestyle for Rural American Indian Youth through Cultural and Physical Activities: A Community-Based Participatory Research StudyP20GM103443 · NIGMS · UNIVERSITY OF SOUTH DAKOTA · PI Ryan Michael Johnson · 2012 to 2026
$58.1M
WESTCORE DNA SEQUENCING AND GENOTYPING CORE FACILITYP20RR016479 · NCRR · UNIVERSITY OF SOUTH DAKOTA · PI EICHLER, BARRETT · 2001 to 2011
$32.2M
Regulation of Streptococcus pyogenes exoproteinsR01AI052147 · NIAID · UNIVERSITY OF SOUTH DAKOTA · PI CHAUSSEE, MICHAEL S · 2004 to 2007
$889k
NCRR NIH HHS 2 P20 RR016479NCRR NIH HHS P20 RR016479NIAID NIH HHS R01 AI052147NIAID NIH HHS R01AI052147NIGMS NIH HHS P20 GM103443
6 · The paper itself

Abstract

Streptococcus pyogenes is an important cause of human morbidity and mortality worldwide. A wealth of genomic information related to this pathogen has facilitated exploration of the proteome, particularly in response to environmental conditions thought to mimic various aspects of pathogenesis. Proteomic approaches are also used to identify immunoreactive proteins for vaccine development and to identify proteins that may induce autoimmunity. These studies have revealed new mechanisms involved in regulating the S. pyogenes proteome, which has opened up new avenues in the study of S. pyogenes pathogenesis. This article describes the methods used, and progress being made towards characterizing the S. pyogenes proteome, including studies seeking to identify potential vaccine candidates.

Indexed as

ProteomeBacterial ProteinsHumansStreptococcal VaccinesStreptococcus pyogenesVirulence FactorsBacterial ProteinsProteomeStreptococcal VaccinesVirulence Factors

Identifiers

PMID21073313
PMCPMC3092638
OpenAlexW1971929733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.