ArticleWorld journal of gastroenterology2010
Patterns of lymph node metastasis are different in colon and rectal carcinomas.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Risk of lymph-node metastasis in early onset T1 colorectal cancer: a systematic review and meta-analysis.Journal of gastroenterology · 2026Pooled it
- Biomarker concordance between primary colorectal cancer and its metastases.EBioMedicine · 2019Pooled it
- Article
- Review
- Artificial Intelligence Models May Aid in Predicting Lymph Node Metastasis in Patients with T1 Colorectal Cancer.Gut and liver · 2025Article
- Predicting lymph node metastasis in colorectal cancer patients: development and validation of a column chart model.Updates in surgery · 2024Article
- Risk of recurrence in high-risk T1 colon cancer following endoscopic and surgical resection: registry-based cohort study.BJS open · 2024Article
- Preoperative endoscopic tattoo marking improves lymph node retrieval in laparoscopic rectal resection: a retrospective cohort study.Annals of coloproctology · 2023Article
- Establishment of a Dynamic Nomogram for Predicting the Risk of Lymph Node Metastasis in T1 Stage Colorectal Cancer.Frontiers in surgery · 2022Article
- Identification of Predictive Factors for Lymph Node Metastasis in pT1 Stage Colorectal Cancer Patients: A Retrospective Analysis Based on the Population Database.Pathology oncology research : POR · 2022Article
- Tumor Location as a Prognostic Factor in T1 Colorectal Cancer.Journal of the anus, rectum and colon · 2022Review
- Risk Stratification of T1 Colorectal Cancer Metastasis to Lymph Nodes: Current Status and Perspective.Gut and liver · 2021Review
- MicroRNA signatures associated with lymph node metastasis in intramucosal gastric cancer.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Article
- Age and Lymph Node Positivity in Patients With Colon and Rectal Cancer in the US Military Health System.Diseases of the colon and rectum · 2020Article
- Overall treatment outcome - analysis of long-term results of rectal cancer treatment on the basis of a new parameter.Archives of medical science : AMS · 2020Article
- Can factors that influence nodal dissemination in patients with colorectal cancer be identified? Own experience.Przeglad gastroenterologiczny · 2020Article
- Pathological risk factors and predictive endoscopic factors for lymph node metastasis of T1 colorectal cancer: a single-center study of 846 lesions.Journal of gastroenterology · 2019Article
- Risk factors of recurrence in T1 colorectal cancers treated by endoscopic resection alone or surgical resection with lymph node dissection.International journal of colorectal disease · 2018Article
- Long-term and Perioperative Outcomes of Laparoscopic and Open Surgery for Rectal Cancer.Sisli Etfal Hastanesi tip bulteni · 2018Article
- Livin serves as a prognostic marker for mid-distal rectal cancer and a target of mid-distal rectal cancer treatment.Oncology letters · 2017Article
Corrections and comments
- Commented on by
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo describe patterns of lymph node metastasis in invasive colon and rectal carcinomas.
methodsClinical data of 2340 patients with colorectal carcinoma (stage I to III) who received radical resection, was retrospectively reviewed. Of the 2340 patients, 1314 patients suffered from rectal carcinoma and 1026 from colon carcinoma. Patients with rectal cancer who received neoadjuvant chemoradiation therapy were excluded. Statistical analysis was performed using Mann-Whitney, χ(2) and Cochran's and Mantel-Haenszel tests (SPSS 15.0). A two-tailed P < 0.05 was considered statistically significant.
resultsLymph node retrieval in the rectal carcinoma group was significantly lower than that in the colon carcinoma group (P < 0.001), while positive lymph node retrieval in the rectal carcinoma group was significantly higher than that in the colon carcinoma group (P < 0.001). The proportion of lymph node positive (N+) cases was higher (patients with one or more positive lymph nodes) in the rectal carcinoma group (P = 0.004). The number of N+ cases was compared at different T stages (T1-T4) to eliminate background bias and the results were confirmed (P < 0.001). In addition, the lymph node ratio (the ratio of number of positive lymph nodes over the number of lymph nodes examined) of stage III cases in the rectal carcinoma group was significantly higher than that in the colon carcinoma group (P < 0.001).
conclusionRectal carcinomas seem more prone to metastasize to the lymph nodes than colon carcinomas, which may be of potential clinical significance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.