ArticleMolecular biology reports2011
Analysis on the interaction between IL-1F7 gene and environmental factors on patients with ankylosing spondylitis: a case-only study.
Article in Molecular biology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Pooled it
- Interleukin-37: associations of plasma levels and genetic variants in gout.Arthritis research & therapy · 2023Article
- Biology of interleukin-37 and its role in autoimmune diseases (Review).Experimental and therapeutic medicine · 2022Review
- The rs6427384 and rs6692977 Single Nucleotide Polymorphisms of the Fc Receptor-Like 5 (FCRL5) Gene and the Risk of Ankylosing Spondylitis: A Case Control Study in a Single Center in China.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Ankylosing spondylitis is associated with aberrant DNA methylation of IFN regulatory factor 8 gene promoter region.Clinical rheumatology · 2019Article
- Cynomolgus macaque IL37 polymorphism and control of SIV infection.Scientific reports · 2019Article
- Relationship between diet and ankylosing spondylitis: A systematic review.European journal of rheumatology · 2018Review
- Common genetic heterogeneity of human interleukin-37 leads to functional variance.Cellular & molecular immunology · 2017Article
- Genomic Variant in IL-37 Confers A Significant Risk of Coronary Artery Disease.Scientific reports · 2017Article
- IL-37 Confers Protection against Mycobacterial Infection Involving Suppressing Inflammation and Modulating T Cell Activation.PloS one · 2017Article
- Genetic analysis of innate immunity in Behcet's disease identifies an association with IL-37 and IL-18RAP.Scientific reports · 2016Article
- Suppression of innate inflammation and immunity by interleukin-37.European journal of immunology · 2016Review
- Interleukin-37 gene variants segregated anciently coexist during hominid evolution.European journal of human genetics : EJHG · 2015Article
- Case-only designs for exploring the interaction between FCRL4 gene and suspected environmental factors in patients with ankylosing spondylitis.Inflammation · 2015Article
- Lack of association between TESPA1 gene polymorphisms (rs1801876, rs2171497, rs4758994, and rs997173) and ankylosing spondylitis in a Chinese population.Inflammation · 2014Article
- Association of FCRL4 polymorphisms on disease susceptibility and severity of ankylosing spondylitis in Chinese Han population.Clinical rheumatology · 2012Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To examine the interaction between IL-1F7 gene and environmental factors in patients with ankylosing spondylities (AS). 150 AS Han Chinese patients (all human leukocyte antigen-B27 positive) were genotyped using a panel of single-nucleotide polymorphism markers within IL-1F7 gene (rs3811047) by ligase detection reactions. Polymerase chain reaction with sequence-specific primer was used to determine HLA-B27 subtypes. We analyzed the interaction between IF-1F7 gene and eight environmental factors in AS patients by using a case-only study. The genetic polymorphism and environmental factors were considered as dependent variables in logistic models, and P-values, ORi and 95% confidence intervals were used for estimating the effects of interaction. The different frequency of A/G between drinking group and non-drinking group was significant (ORi 3.163, 95% CI 1.368-7.317, P=0.006). Within the cooking oil group, odds ratio for interaction of G×E between main plants fats and half plants -half animal fats subunits was 4.273 (95% CI 1.590-11.479, P=0.004). Our data show that there was no interaction between IL-1F7 alleles and the other six environmental factors in AS patients (all P>0.05). We observed that there was an interaction between IF-1F7 gene and drinking in AS patients. Thus, drinking may be a risk exposure factor to take combined action with predisposing genes in AS patients. This action may increase the incident risk of AS. Also, main plants fats may be protective factors to AS.
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