ArticleMedical microbiology and immunology2011
Monitoring prevalence of varicella-zoster virus clades in Germany.
Article in Medical microbiology and immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Review
- Seropositivity of Varicella zoster virus in vaccinated Korean children and MAV vaccine group.Human vaccines & immunotherapeutics · 2016Article
- Diagnosis, antiviral therapy, and prophylaxis of varicella-zoster virus infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Review
- Varicella-zoster virus infections - antiviral therapy and diagnosis.GMS infectious diseases · 2016Review
- Rates of vaccine evolution show strong effects of latency: implications for varicella zoster virus epidemiology.Molecular biology and evolution · 2015Article
- Fifteen years of routine childhood varicella vaccination in the United States-strong decrease in the burden of varicella disease and no negative effects on the population level thus far.Translational pediatrics · 2014Article
- Use of oral fluid to examine the molecular epidemiology of varicella zoster virus in the United Kingdom and continental Europe.The Journal of infectious diseases · 2013Article
- Recent publications in medical microbiology and immunology: a retrospective.Medical microbiology and immunology · 2012Review
- Sequencing of 21 varicella-zoster virus genomes reveals two novel genotypes and evidence of recombination.Journal of virology · 2012Article
- Varicella Outbreak in an Indian Couple Living in Germany Caused by VZV Clade VI Acquired during a Trip to The Netherlands.Case reports in medicine · 2012Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global surveillance of varicella-zoster virus (VZV) clades is an important tool for investigation into viral evolution, host-virus interactions, role of immigration and travel for importation of viral strains as well as possible recombination events between wild- and vaccine-type VZV strains. In this prospective study, comprehensive data on the current distribution of VZV clades in Germany were collected. VZV strains from 213 patients with varicella and 109 with zoster were genotyped using the scattered single-nucleotide polymorphism method on the basis of sequencing open reading frames 1, 21, 22, 37, 50, 54 and 60. In varicella, clade 3 was detected in 45.5%, clade 1 in 30.0%, clade 5 in 21.1% and clade 2 in 0.9% of the cases. The analysis of zoster strains revealed clade 3 in 50.5%, clade 1 in 46.8%, clade 2 and clade 4 in 0.9% of the cases each. Five strains from varicella and one strain from zoster could not be attributed to any of the major and provisional VZV clades. Statistical analysis verified significantly lower frequency of clade 1 and significantly higher frequency of clade 5 in patients with varicella compared to zoster. In addition, varicella patients with clade 5 strains were significantly younger than the patients with clade 3. In conclusion, almost one half of VZV infections in Germany were caused currently by VZV clade 3. In primary VZV infection, nearly 20% of clade 1 has been replaced by clade 5 that might spread more effectively in the population than the European VZV clades.
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