ArticleInternational journal of women's health2010
Advances in labor analgesia.
Article in International journal of women's health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Neuraxial Labor Analgesia on the Incidence of Postpartum Depression: a Prospective, Observational, Multicenter Cohort Study
Evaluation of the Effectiveness of Transcutaneous Electrical Nerve Stimulation During Labor. A Triple Blind Randomized Clinical Trial
Impact of Maternal Neuraxial Labor Analgesia on Offspring Neurodevelopment. A Multicenter, Prospective, Longitudinal Cohort Study
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 169 citations in OpenAlex.
- Parenteral opioids for maternal pain management in labour.The Cochrane database of systematic reviews · 2018Pooled it
- Trial
- The effects of transcutaneous electrical nerve stimulation during the first stage of labor: a randomized controlled trial.BMC pregnancy and childbirth · 2021Trial
- Effect of led photobiomodulation on analgesia during labor: Study protocol for a randomized clinical trial.Medicine · 2018Trial
- Comparison Between the Use of Ropivacaine Alone and Ropivacaine With Sufentanil in Epidural Labor Analgesia.Medicine · 2015Trial
- Effects of continuous use of Entonox in comparison with intermittent method on obstetric outcomes: a randomized clinical trial.Journal of pregnancy · 2014Trial
- Comparison of 0.1% Ropivacaine and 0.0625% Bupivacaine With Fentanyl as an Adjuvant for Labour Analgesia.Cureus · 2026Article
- Development and validation of a risk nomogram for failed conversion from labor epidural analgesia to cesarean epidural anesthesia.Frontiers in medicine · 2026Article
- Association of remifentanil analgesia with postpartum depression and birth experience: an observational study.BMC pregnancy and childbirth · 2025Observational
- Administering intrathecal sufentanil during the second stage of labor: impact on duration.Annals of medicine and surgery (2012) · 2025Article
- Article
- Effectiveness of staged nursing in reducing labor analgesia complications: a retrospective cohort study.Frontiers in medicine · 2025Article
- The effects of ear acupressure therapy on obstetric and gynecological pain in women: a systematic review and meta-analysis.Journal of Korean biological nursing science · 2024Review
- Article
- Determinants and willingness to practice obstetric analgesia among women attending antenatal clinic at Dr. Bogalech Gebre Memorial General Hospital Central Ethiopia: a cross-sectional study.BMC pregnancy and childbirth · 2024Article
- The Management of Spinal and Epidural Anesthesia-Related Hypotension in the United States During Cesarean Childbirth.Cureus · 2024Review
- Pelvic Ring Fracture Management and Subsequent Pregnancy: A Summary of Current Literature.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024Article
- A Pharmacotherapeutic Approaches for Managing Labour Pain Using Synthetic Drugs and Natural Therapies.Combinatorial chemistry & high throughput screening · 2024Review
- The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia.Local and regional anesthesia · 2024Article
- Non-Pharmacological Pain Management in Labor: A Systematic Review.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pain of childbirth is arguably the most severe pain most women will endure in their lifetimes. The pain of the early first stage of labor arises from dilation of the lower uterine segment and cervix. Pain from the late first stage and second stage of labor arises from descent of the fetus in the birth canal, resulting in distension and tearing of tissues in the vagina and perineum. An array of regional nerve blocks, systemic analgesic, and nonpharmacologic techniques are currently used for labor analgesia. Nonpharmacologic methods are commonly used, but the effectiveness of these techniques generally lacks rigorous scientific study. Continuous labor support has been shown to decrease the use of pharmacologic analgesia and shorten labor. Intradermal water injections decrease back labor pain. Neuraxial labor analgesia (most commonly epidural or combined spinal-epidural) is the most effective method of pain relief during childbirth, and the only method that provides complete analgesia without maternal or fetal sedation. Current techniques commonly combine a low dose of local anesthetic (bupivacaine or ropivacaine) with a lipid soluble opioid (fentanyl or sufentanil). Neuraxial analgesia does not increase the rate of cesarean delivery compared to systemic opioid analgesia; however, dense neuraxial analgesia may increase the risk of instrumental vaginal delivery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.