ArticleInternational journal of women's health2010
Safety, efficacy and patient acceptability of the contraceptive and non-contraceptive uses of the LNG-IUS.
Article in International journal of women's health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 68 citations in OpenAlex.
- Life-Threatening Ectopic Pregnancy Implanted on the Uterosacral Ligament in a LNG-IUS User: A Maternal Near-Miss Event.Case reports in obstetrics and gynecology · 2026Article
- Population characteristics of intrauterine device users in real-world clinical practice across Europe - insights from the EURAS-LCS12 study.Contraception and reproductive medicine · 2025Article
- Perceptions of access to long-acting reversible contraception removal among women in Burkina Faso.Contraception · 2024Article
- Utility of the Levonorgestrel-Releasing Intrauterine System in the Treatment of Abnormal Uterine Bleeding and Dysmenorrhea: A Narrative Review.Journal of clinical medicine · 2022Article
- Observational study of feasibility and acceptability of the levonorgestrel-releasing intrauterine device as a long-acting reversible contraceptive in a primary care setting in India.Contraception: X · 2022Article
- Article
- Digital Medical Device Companion (MyIUS) for New Users of Intrauterine Systems: App Development Study.JMIR medical informatics · 2021Article
- Expanding Contraceptive Method Choice With a Hormonal Intrauterine System: Results From Mixed Methods Studies in Kenya and Zambia.Global health, science and practice · 2021Article
- Impact of Combined Hormonal Contraceptive Use on Weight Loss: A Secondary Analysis of a Behavioral Weight-Loss Trial.Obesity (Silver Spring, Md.) · 2020Article
- Clinical Efficacy and Safety of Major Uterine Wall Resection and Reconstruction of the Uterus Combined with LNG-IUS for the Treatment of Severe Adenomyosis.Geburtshilfe und Frauenheilkunde · 2020Article
- Depressive Disorder With Panic Attacks After Replacement of an Intrauterine Device Containing Levonorgestrel: A Case Report.Frontiers in psychiatry · 2020Article
- Clinical efficacy of adenomyomectomy using "H" type incision combined with Mirena in the treatment of adenomyosis.Medicine · 2019Article
- A Global Learning Agenda for the Levonorgestrel Intrauterine System (LNG IUS): Addressing Challenges and Opportunities to Increase Access.Global health, science and practice · 2018Article
- Experiences with the levonorgestrel-releasing intrauterine system in Kenya: qualitative interviews with users and their partners.The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception · 2018Article
- Postpartum intrauterine device placement: a patient-friendly option.Contraception and reproductive medicine · 2018Review
- The comorbidities of dysmenorrhea: a clinical survey comparing symptom profile in women with and without endometriosis.Journal of pain research · 2018Article
- Medically induced amenorrhea in female astronauts.NPJ microgravity · 2016Review
- New developments in intrauterine device use: focus on the US.Open access journal of contraception · 2016Review
- Understanding benefits and addressing misperceptions and barriers to intrauterine device access among populations in the United States.Patient preference and adherence · 2014Review
- Levonorgestrel intrauterine system as a treatment option for severe menorrhagia in adolescent with type III von Willebrand disease.BMJ case reports · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intrauterine devices (IUDs) provide highly effective, long-term, safe, reversible contraception, and are the most widely used reversible contraceptive method worldwide. The levonorgestrel-releasing intrauterine system (LNG-IUS) is a T-shaped IUD with a steroid reservoir containing 52 mg of levonorgestrel that is released at an initial rate of 20 μg daily. It is highly effective, with a typical-use first year pregnancy rate of 0.1% - similar to surgical tubal occlusion. It is approved for 5 years of contraceptive use, and there is evidence that it can be effective for up to 7 years of continuous use. After removal, there is rapid return to fertility, with 1-year life-table pregnancy rates of 89 per 100 for women less than 30 years of age. Most users experience a dramatic reduction in menstrual bleeding, and about 15% to 20% of women become amenorrheic 1 year after insertion. The device's strong local effects on the endometrium benefit women with various benign gynecological conditions such as menorrhagia, dysmenorrhea, leiomyomata, adenomyosis, and endometriosis. There is also evidence to support its role in endometrial protection during postmenopausal estrogen replacement therapy, and in the treatment of endometrial hyperplasia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.