ArticleAging2010
Environmental cadmium and breast cancer risk.
Article in Aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 3 syntheses or guidelines pooled it, 166 citations in OpenAlex.
- Cadmium exposure and risk of breast cancer: A meta-analysis.Environmental research · 2023Pooled it
- Blood levels of cadmium and lead in relation to breast cancer risk in three prospective cohorts.International journal of cancer · 2019Pooled it
- Pooled it
- M-Type Strontium Hexaferrite Nanoestructures Derived from the Pechini Method as Magnetically Hard Adsorbents for Cadmium Removal in Aqueous Solution.Materials (Basel, Switzerland) · 2026Article
- DNA damage response inhibition is an early event in cadmium-induced breast carcinogenesis.Toxicology and applied pharmacology · 2025Article
- Mechanistic study of the adsorption capabilities of heavy metals on the surface of ferrihydrite: batch sorption, modeling, and density functional theory.RSC advances · 2025Article
- Heavy-metal associated breast cancer and colorectal cancer hot spots and their demographic and socioeconomic characteristics.Cancer causes & control : CCC · 2024Article
- Carcinogenic industrial air pollution and postmenopausal breast cancer risk in the National Institutes of Health AARP Diet and Health Study.Environment international · 2024Article
- Toxicity Tolerance in the Carcinogenesis of Environmental Cadmium.International journal of molecular sciences · 2024Review
- Assessment of salivary cadmium levels and breast density in the Marin Women's Study.Cancer medicine · 2024Article
- Association of air pollution with postmenopausal breast cancer risk in UK Biobank.Breast cancer research : BCR · 2023Article
- Probabilistic risk assessment of residential exposure to metal(loid)s in a mining impacted community.The Science of the total environment · 2023Article
- Estimation of health risks associated with dietary cadmium exposure.Archives of toxicology · 2023Review
- Metals and Breast Cancer Risk: A Prospective Study Using Toenail Biomarkers.American journal of epidemiology · 2021Article
- Developmental toxicity of cadmium in infants and children: a review.Environmental analysis, health and toxicology · 2021Article
- Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014 to 2017.BMC cancer · 2020Article
- Review
- Meta-analysis of gene expression profiling reveals novel basal gene signatures in MCF-10A cells transformed with cadmium.Oncotarget · 2020Article
- Metals and molecular carcinogenesis.Carcinogenesis · 2020Review
- Arsenite and cadmium promote the development of mammary tumors.Carcinogenesis · 2020Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is the most prevalent women's cancer, with an age-adjusted incidence of 122.9 per 100,000 US women. Cadmium, a ubiquitous carcinogenic pollutant with multiple biological effects, has been reported to be associated with breast cancer in one US regional case-control study. We examined the association of breast cancer with urinary cadmium (UCd), in a case-control sample of women living on Long Island (LI), NY (100 with breast cancer and 98 without), a region with an especially high rate of breast cancer (142.7 per 100,000 in Suffolk County) and in a representative sample of US women (NHANES 1999-2008, 92 with breast cancer and 2,884 without). In a multivariable logistic model, both samples showed a significant trend for increased odds of breast cancer across increasing UCd quartiles (NHANES, p=0.039 and LI, p=0.023). Compared to those in the lowest quartile, LI women in the highest quartile had increased risk for breast cancer (OR=2.69; 95% CI=1.07, 6.78) and US women in the two highest quartiles had increased risk (OR=2.50; 95% CI=1.11, 5.63 and OR=2.22; 95% CI=.89, 5.52, respectively). Further research is warranted on the impact of environmental cadmium on breast cancer risk in specific populations and on identifying the underlying molecular mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.