ReviewArteriosclerosis, thrombosis, and vascular biology2010
Platelet-leukocyte interactions in cardiovascular disease and beyond.
Review in Arteriosclerosis, thrombosis, and vascular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 1 synthesis or guideline pooled it, 251 citations in OpenAlex.
- Platelet-associated parameters in patients with psoriasis: A PRISMA-compliant systematic review and meta-analysis.Medicine · 2021Pooled it
- Relationship of Platelet Counts and Inflammatory Markers to 30-Day Mortality Risk in Patients with Acute Type A Aortic Dissection.BioMed research international · 2020Trial
- Effect of Hypoglycemia on Inflammatory Responses and the Response to Low-Dose Endotoxemia in Humans.The Journal of clinical endocrinology and metabolism · 2019Trial
- Novel Biomarkers for Coronary Restenosis Occurrence After Drug-Eluting Stent Implantation in Patients With Diabetes Having Stable Coronary Artery Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018Trial
- Platelet-Neutrophil interactions inVirulence · 2026Article
- From Inflammation to Targeted Therapy: Leveraging Neutrophil, Platelet, RBC, and Macrophage Biology for Nanocarrier in Atherosclerosis.Current atherosclerosis reports · 2026Review
- CCL5 promotes angiotensin II-induced cardiac remodeling through regulation of platelet-driven M2 macrophage polarization.Theranostics · 2026Article
- Construction and validation of a prediction model for in-stent restenosis following coronary stent implantation during dual antiplatelet therapy.Frontiers in cardiovascular medicine · 2026Article
- Supernatants from stored platelet concentrates modulate the inflammatory response in platelet-depleted blood ex vivo.Frontiers in immunology · 2026Article
- Inhibiting Monocyte Migration Reduces Arterial Thrombosis and Facilitates Thrombolysis.Stroke · 2025Article
- Platelet-derived biomimetic nanoplatforms: a promising drug delivery strategy for cardiovascular disease.Journal of nanobiotechnology · 2025Review
- Article
- Thrombocytopenia in patients with inborn errors of immunity.BMC immunology · 2025Article
- Association of systemic immune-inflammation index with adverse outcomes in heart failure and preserved ejection fraction.Journal of translational medicine · 2025Article
- Evidence for control of cerebral neurovascular function by circulating platelets in healthy older adults.The Journal of physiology · 2025Article
- Observational
- Protocol for assessing and visualizing cell microaggregate formation in whole blood by imaging flow cytometry.STAR protocols · 2025Article
- Association between systemic inflammation markers and blood pressure among children and adolescents: National Health and Nutrition Examination Survey.Pediatric research · 2025Article
- Prognostic implications of system inflammation response index in atrial fibrillation patients with type 2 diabetes mellitus.Scientific reports · 2025Article
- Prognostic Value of the Preoperative Lymphocyte-to-Monocyte Ratio for Postoperative Adverse Events in Patients with Acute Type a Aortic Dissection.Journal of inflammation research · 2025Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Platelet-leukocyte interactions define a basic cell process that is characterized by the exchange of signals between platelets and different types of leukocytes and that bridges 2 fundamental pathophysiological events: atherothrombosis and inflammatory immune reactions. When this process takes place at the site of atherosclerotic plaque development or at the site of endothelial injury, platelet-dependent leukocyte recruitment and activation contributes to the inflammatory reaction of the vessel wall, which accounts for the exacerbation of atherosclerosis and for intimal hyperplasia and plaque instability. Moreover, platelet-leukocyte interactions may have a key role in modulating a wide array of responses of both the innate and adaptive immune systems, thus contributing to the pathogenesis of inflammatory diseases and tissue damage, as well as to host defense.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.