ReviewClinical and experimental immunology2010
Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories.
Review in Clinical and experimental immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Biological risk assessment related to intracerebral injection of TMEV-DA.Archives of virology · 2026Article
- Facing the challenges of multidrug-resistantHuman vaccines & immunotherapeutics · 2021Article
- Loss of Interleukin-6 Influences Transcriptional Immune Signatures and Alters Bacterial Colonization in the Skin.Frontiers in microbiology · 2021Article
- Susceptibility Analysis in Several Mouse Strains Reveals Robust T-Cell Responses AfterFrontiers in cellular and infection microbiology · 2020Article
- TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected withInternational journal of microbiology and current research · 2019Article
- The impact of host genetic background in the Pseudomonas aeruginosa respiratory infections.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Review
- Autoimmune-Disease-Prone NOD Mice Help To Reveal a New Genetic Locus for Reducing Pulmonary Disease Caused by Mycoplasma pulmonis.Infection and immunity · 2018Article
- The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection.Scientific reports · 2016Article
- Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice.BMC genomics · 2016Article
- A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.PLoS pathogens · 2014Article
- Article
- Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages.Immunology and cell biology · 2013Article
- R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea.Nature communications · 2013Article
- Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice.F1000Research · 2013Article
- Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains.Respiratory research · 2012Article
- Living with the enemy or uninvited guests: functional genomics approaches to investigating host resistance or tolerance traits to a protozoan parasite, Theileria annulata, in cattle.Veterinary immunology and immunopathology · 2012Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mouse genetics is a powerful tool for the dissection of genes, proteins, and pathways important in biological processes. Application of this approach to study the host response to infection has been a rich source of discoveries that have increased our understanding of the early innate pathways involved in responding to microbial infections. Here we review some of the key discoveries that have arisen from pinpointing the genetic defect in mouse strains with unusual or extreme response to infection and have led to insights into pathogen sensing pathways and downstream effector functions of the early innate immune response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.