ReviewInternational orthopaedics2011
New animal models of wear-particle osteolysis.
Review in International orthopaedics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Arthrotomy-based preclinical models of particle-induced osteolysis: A systematic review.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017Pooled it
- A Murine Model of Non-Wear-Particle-Induced Aseptic Loosening.Biomimetics (Basel, Switzerland) · 2024Article
- Increased UHMWPE Particle-Induced Osteolysis in Fetuin-A-Deficient Mice.Journal of functional biomaterials · 2023Article
- Exosomes From Human Urine-Derived Stem Cells Encapsulated Into PLGA Nanoparticles for Therapy in Mice With Particulate Polyethylene-Induced Osteolysis.Frontiers in medicine · 2021Article
- The Effects of Biomaterial Implant Wear Debris on Osteoblasts.Frontiers in cell and developmental biology · 2020Review
- Construction and Evaluation of a Murine Calvarial Osteolysis Model by Exposure to CoCrMo Particles in Aseptic Loosening.Journal of visualized experiments : JoVE · 2018Article
- Curcumin Attenuation of Wear Particle-Induced Osteolysis via RANKL Signaling Pathway Suppression in Mouse Calvarial Model.Mediators of inflammation · 2017Article
- The Role of the Chemokine System in Tissue Response to Prosthetic By-products Leading to Periprosthetic Osteolysis and Aseptic Loosening.Frontiers in immunology · 2017Review
- Surgical Modification of the Murine Calvaria Osteolysis Model.BioMed research international · 2015Article
- Direct subcutaneous injection of polyethylene particles over the murine calvaria results in dramatic osteolysis.International orthopaedics · 2013Article
- Local effect of IL-4 delivery on polyethylene particle induced osteolysis in the murine calvarium.Journal of biomedical materials research. Part A · 2013Article
- Characteristics of highly cross-linked polyethylene wear debris in vivo.Journal of biomedical materials research. Part B, Applied biomaterials · 2013Article
- Adenosine A2A receptor activation prevents wear particle-induced osteolysis.Science translational medicine · 2012Article
- Retention of a well-fixed acetabular component in the setting of acetabular osteolysis.International orthopaedics · 2012Article
- Total Hip Arthroplasty, state of the art for the 21st century.International orthopaedics · 2011Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Particle debris resulting from in vivo degradation of total joint replacement components are recognised as the major factor limiting the longevity of joint reconstruction and the overall success of the procedure. Better understanding the complex cellular and tissue mechanisms and interactions resulting in wear-particle osteolysis requires a number of experimental approaches, including radiological monitoring and analysis of retrieved tissues from clinical cases, in vitro experiments, and also animal-model investigations. In consideration of both their advantages and drawbacks, this paper provides an historical overview of numerous animal models that have been developed over the last three decades to investigate the pathogenesis of wear-particle osteolysis and to facilitate the preclinical testing of new treatment options. The authors also focus on recent studies in order to provide a better understanding of the current state of the art on this subject and propose some perspectives regarding technical and fundamental questions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.