ArticleEuropean journal of clinical pharmacology2011
Prescribed-drug utilization and polypharmacy in a general population in Greece: association with sociodemographic, health needs, health-services utilization, and lifestyle factors.
Article in European journal of clinical pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 63 citations in OpenAlex.
- Determinants of polypharmacy among ambulatory cardiovascular disease patients in Iluababora and Buno Bedele Zones, Ethiopia: prospective observational study.BMC cardiovascular disorders · 2025Observational
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- Characteristics of High-Cost Beneficiaries of Prescription Drugs in Kazakhstan: A Cross-Sectional Study of Outpatient Data from 2022.ClinicoEconomics and outcomes research : CEOR · 2024Article
- Prevalence and Correlates of Polypharmacy, and Drug Utilization Pattern in a Semi-urban Population: Results from the Pars Cohort Study.Archives of Iranian medicine · 2023Article
- Prevalence and Predicting Risk Factors of Polypharmacy in Azar Cohort Population.Iranian journal of pharmaceutical research : IJPR · 2022Article
- High-Cost Users of Prescription Drugs: National Health Insurance Data from South Korea.Journal of general internal medicine · 2022Observational
- Risk prediction model of polypharmacy for community-dwelling elderly patients: An assessment tool for early detection.Frontiers in pharmacology · 2022Article
- Maintenance Therapy of Psychosis Spectrum Disorders in a Real-World Setting: Antipsychotics Prescription Patterns and Long-Term Benzodiazepine Use.Frontiers in psychiatry · 2022Article
- Analysis of the regional difference in the number of multi-drug prescriptions and its predictors in Japan, 2015-2018.BMC research notes · 2021Article
- The Double Burden of the COVID-19 Pandemic and Polypharmacy on Geriatric Population - Public Health Implications.Therapeutics and clinical risk management · 2020Review
- Prevalence and determinants of polypharmacy in cardiovascular patients attending outpatient clinic in Ethiopia University Hospital.PloS one · 2020Article
- Socio-economic and behavioral determinants of prescription and non-prescription medicine use: the case of Turkey.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019Article
- Polypharmacy in Patients with Ovarian Cancer.The oncologist · 2019Article
- Effective Factors of Utilization of Inpatient, Outpatient, Diagnostic, and Pharmaceutical Health Services: A Systematic Review.Galen medical journal · 2019Review
- Influence of Education Level of Older Patients on Polypharmacy, Potentially Inappropriate Medications Listed in Beer's Criteria, and Unplanned Hospitalization: A Cross-Sectional Study in Lahore, Pakistan.Medicina (Kaunas, Lithuania) · 2018Article
- Assessment of prescribing potentially inappropriate medications listed in Beers criteria and its association with the unplanned hospitalization: a cross-sectional study in Lahore, Pakistan.Clinical interventions in aging · 2018Observational
- Prevalence and determinants of polypharmacy in Switzerland: data from the CoLaus study.BMC health services research · 2017Article
- Determinants of change in polypharmacy status in Switzerland: the population-based CoLaus study.European journal of clinical pharmacology · 2017Article
- Drug utilization patterns among elderly hospitalized patients on poly-pharmacy in Punjab, Pakistan.Journal of pharmaceutical policy and practice · 2017Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOur aim was to analyze, in a multivariate framework, how sociodemographic, health-service utilization, health needs, and lifestyle risk factors influence drug utilization and polypharmacy (PP) in a general population in Greece.
methodsThe cross-sectional study took place in 2006. In total 1,005 individuals (> 18 years old) of 1,388 who were approached (response rate 72.4%) were interviewed by trained interviewers. Thirty-seven reported only over-the-counter (OTC) drug use and were excluded. The final sample was 968 individuals. Multivariable logistic regression and multinomial regression analyses were conducted to determine the predictors of drug use and PP at a significance level of p < 0.05.
resultsThe results revealed a high rate of drug use and PP. Drug use and PP were more common among women and increased with age. Advanced age 65+ [odds ratio (OR) 11.6), university education (OR 2.3), visits to physician (OR 2.2), comorbidity (OR 6.8), or poor physical and mental health were associated with higher likelihood of using drugs. Minor (two to three drugs) and major (four or more drugs) PP depended on comorbidity, physical health, and increased age. Furthermore, visits to physicians (OR 1.1), smoking (OR 3.0), and obesity (OR 3.8) increased the likelihood of major PP.
conclusionsOverall, drug utilization and PP depended on health needs followed by education, utilization of health services, and age. Social disparities do persist and, after adjustments for health needs and obesity, had a significant influence on PP.
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