Evidence map›Paper›PMID 21068290›Full record

ArticleJournal of clinical microbiology2011

Breakthrough Hormographiella aspergillata infections arising in neutropenic patients treated empirically with caspofungin.

Felipe Suarez, Gaelle Olivier, Dea Garcia-Hermoso, Edouard Randriamalala, David Ghez, Julie Bruneau, Catherine Kauffmann-Lacroix, Marie-Elisabeth Bougnoux, Olivier Lortholary

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. The first suspected disseminatedEmerging microbes & infections · 2023
    Article
  3. Review
  4. Successful Treatment of Rare PulmonaryInfection and drug resistance · 2023
    Article
  5. InvasiveAnnals of laboratory medicine · 2022
    Article
  6. InvasiveMedical mycology case reports · 2021
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Filamentous Basidiomycetes in the Clinical Laboratory.Current fungal infection reports · 2013
    Article
  14. Excavated pneumonia: an unusual suspect.Intensive care medicine · 2013
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Felipe SuarezUniversité Paris Descartes, Service d'Hématologie Adultes, Hôpital Necker-Enfants Malades, AP-HP, 149 Rue de Sèvres, 75743 Paris Cedex 15, France. felipe.suarez@nck.aphp.fr
Gaelle Olivier
Dea Garcia-Hermoso
Edouard Randriamalala
David Ghez
Julie Bruneau
Catherine Kauffmann-Lacroix
Marie-Elisabeth Bougnoux
Olivier Lortholary
Centre Hospitalier Universitaire de Poitiers · FRHôpital Necker-Enfants Malades · FRAssistance Publique – Hôpitaux de Paris · FRCentre National de la Recherche Scientifique · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hormographiella aspergillata, a filamentous basidiomycete, has rarely been involved in human infections. We describe 2 febrile neutropenic patients who developed a severe pulmonary infection due to H. aspergillata while receiving empirical caspofungin therapy for presumed fungal pneumonia. After introduction of liposomal amphotericin B, one patient, who had neutrophil recovery, presented a favorable outcome, while the other, who remained neutropenic throughout the course of infection, died. Resistant fungi, including basidiomycetes, may emerge during empirical treatment with caspofungin in febrile neutropenic patients. A rapid switch to any other potent antifungal should be rapidly considered in case of failure of caspofungin in this setting.

Indexed as

AdultAmphotericin BAntifungal AgentsBasidiomycotaCaspofunginDNA, FungalEchinocandinsFemaleFever of Unknown OriginFungiHumansLipopeptidesLung Diseases, FungalMaleMolecular Sequence DataMycosesAmphotericin BAntifungal AgentsCaspofunginDNA, FungalEchinocandinsLipopeptidesliposomal amphotericin B

Identifiers

PMID21068290
PMCPMC3020423
OpenAlexW2026894433

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.