ArticleJournal of virology2011
Phylogeography of the spring and fall waves of the H1N1/09 pandemic influenza virus in the United States.
Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review to identify areas of enhancements of pandemic simulation models for operational use at provincial and local levels.BMC public health · 2012Pooled it
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- Temporal patterns of influenza A subtypes and B lineages across age in a subtropical city, during pre-pandemic, pandemic, and post-pandemic seasons.BMC infectious diseases · 2019Article
- Association of meteorological factors with seasonal activity of influenza A subtypes and B lineages in subtropical western China.Epidemiology and infection · 2019Article
- Incorporating sampling uncertainty in the geospatial assignment of taxa for virus phylogeography.Virus evolution · 2019Article
- The continual threat of influenza virus infections at the human-animal interface: What is new from a one health perspective?Evolution, medicine, and public health · 2018Review
- Seasonality in risk of pandemic influenza emergence.PLoS computational biology · 2017Article
- Temporal distribution and genetic variants in influenza A(H1N1)pdm09 virus circulating in Mexico, seasons 2012 and 2013.PloS one · 2017Article
- Genetic Characterization of Circulating 2015 A(H1N1)pdm09 Influenza Viruses from Eastern India.PloS one · 2016Article
- Virus evolution and transmission in an ever more connected world.Proceedings. Biological sciences · 2015Review
- Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats.Viruses · 2015Article
- Differential Immune Profiles in Two Pandemic Influenza A(H1N1)pdm09 Virus Waves at Pandemic Epicenter.Archives of medical research · 2015Article
- Phylodynamics of H1N1/2009 influenza reveals the transition from host adaptation to immune-driven selection.Nature communications · 2015Article
- Haemagglutinin mutations and glycosylation changes shaped the 2012/13 influenza A(H3N2) epidemic, Houston, Texas.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2015Article
- The evolutionary dynamics of influenza A and B viruses in the tropical city of Managua, Nicaragua.Virology · 2014Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in humans has been documented throughout the 20th century but never understood at a molecular level. However, the unprecedented intensity of sampling and whole-genome sequencing of the H1N1/09 pandemic virus now makes such an approach possible. To determine whether the spring and fall waves of the H1N1/09 influenza pandemic were associated with different epidemiological patterns, we undertook a large-scale phylogeographic analysis of viruses sampled from three localities in the United States. Analysis of genomic and epidemiological data reveals distinct spatial heterogeneities associated with the first pandemic wave, March to July 2009, in Houston, TX, Milwaukee, WI, and New York State. In Houston, no specific H1N1/09 viral lineage dominated during the spring of 2009, a period when little epidemiological activity was observed in Texas. In contrast, major pandemic outbreaks occurred at this time in Milwaukee and New York State, each dominated by a different viral lineage and resulting from strong founder effects. During the second pandemic wave, beginning in August 2009, all three U.S. localities were dominated by a single viral lineage, that which had been dominant in New York during wave 1. Hence, during this second phase of the pandemic, extensive viral migration and mixing diffused the spatially defined population structure that had characterized wave 1, amplifying the one viral lineage that had dominated early on in one of the world's largest international travel centers.
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