ArticleForensic science international. Genetics2011
Application of a west Eurasian-specific filter for quasi-median network analysis: Sharpening the blade for mtDNA error detection.
Article in Forensic science international. Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Contrasting Maternal, Paternal, and Biparental Ancestry of Populations From the Caribbean Coast of Colombia.American journal of biological anthropology · 2026Article
- Intensive post-war migrations and mtDNA variation based on Poland case.Scientific reports · 2025Article
- Comparisons of aged samples and modern references provide algorithm for mtDNA analysis in challenging material.Scientific reports · 2025Article
- Review: Computational analysis of human skeletal remains in ancient DNA and forensic genetics.iScience · 2023Review
- Environmental DNA as an innovative technique to identify the origins of falsified antimalarial tablets-a pilot study of the pharmabiome.Scientific reports · 2022Article
- Review
- Article
- Improved visibility of character conflicts in quasi-median networks with the EMPOP NETWORK software.Croatian medical journal · 2014Article
- Review
- Evaluation of next generation mtGenome sequencing using the Ion Torrent Personal Genome Machine (PGM).Forensic science international. Genetics · 2013Article
- MtDNA diversity of Ghana: a forensic and phylogeographic view.Forensic science international. Genetics · 2012Article
- Current genetic methodologies in the identification of disaster victims and in forensic analysis.Journal of applied genetics · 2012Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The application of quasi-median networks provides an effective tool to check the quality of mtDNA data. Filtering of highly recurrent mutations prior to network analysis is required to simplify the data set and reduce the complexity of the network. The phylogenetic background determines those mutations that need to be filtered. While the traditional EMPOPspeedy filter was based on the worldwide mtDNA phylogeny, haplogroup-specific filters can more effectively highlight potential errors in data of the respective (sub)-continental region. In this study we demonstrate the performance of a new, west Eurasian filter EMPOPspeedyWE for the fine-tuned examination of data sets belonging to macrohaplogroup N that constitutes the main portion of mtDNA lineages in Europe. The effects on the resulting network of different database sizes, high-quality and flawed data, as well as the examination of a phylogenetically distant data set, are presented by examples. The analyses are based on a west Eurasian etalon data set that was carefully compiled from more than 3500 control region sequences for network purposes. Both, etalon data and the new filter file, are provided through the EMPOP database (www.empop.org).
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