ReviewBreast cancer research : BCR2010
Role of dietary fatty acids in mammary gland development and breast cancer.
Review in Breast cancer research : BCR, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Obesity and Risk of Pre- and Postmenopausal Breast Cancer in Africa: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Association of Dietary Intake Ratio of n-3/n-6 Polyunsaturated Fatty Acids with Breast Cancer Risk in Western and Asian Countries: A Meta-AnalysisAsian Pacific journal of cancer prevention : APJCP · 2019Pooled it
- Ratio of n-3/n-6 PUFAs and risk of breast cancer: a meta-analysis of 274135 adult females from 11 independent prospective studies.BMC cancer · 2014Pooled it
- LifelongNutrients · 2026Article
- Omega-3 Fatty Acids Regulate Mammary Gland Lipogenesis and Development via GαResearch (Washington, D.C.) · 2025Article
- The association of preoperative serum free fatty acid levels with survival in breast cancer patients.Discover oncology · 2024Article
- Identification of circulating metabolites linked to the risk of breast cancer: a mendelian randomization study.Frontiers in pharmacology · 2024Article
- Fatty acid traits mediate the effects of uric acid on cancers: a Mendelian randomization study.Frontiers in genetics · 2024Article
- Promising Effects ofMolecules (Basel, Switzerland) · 2023Review
- Chemical Composition and Cytotoxic Activity of the Essential Oil and Oleoresins of In Vitro MicropropagatedMolecules (Basel, Switzerland) · 2021Article
- Growth inhibitory and anti-metastatic activity of epithelial cell adhesion molecule targeted three-way junctional delta-5-desaturase siRNA nanoparticle for breast cancer therapy.Nanomedicine : nanotechnology, biology, and medicine · 2020Article
- Pubertal mammary development as a "susceptibility window" for breast cancer disparity.Advances in cancer research · 2020Review
- Article
- Association of Overweight and Obesity with Breast Cancer During Premenopausal Period in Asia: A Meta-Analysis.International journal of preventive medicine · 2019Review
- Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway.Nutrients · 2018Article
- Causal Inference in Cancer Epidemiology: What Is the Role of Mendelian Randomization?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Review
- Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation.Journal of mammary gland biology and neoplasia · 2018Article
- Breast cancer is associated to impaired glucose/insulin homeostasis in premenopausal obese/overweight patients.Oncotarget · 2017Article
- Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention.Oncotarget · 2017Article
- Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk.Endocrine-related cancer · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Breast cancer is the most common cancer among women worldwide. Estimates suggest up to 35% of cases may be preventable through diet and lifestyle modification. Growing research on the role of fats in human health suggests that early exposure in life to specific fatty acids, when tissues are particularly sensitive to their environment, can have long-term health impacts. The present review examines the role of dietary fat in mammary gland development and breast cancer throughout the lifecycle. Overall, n-3 polyunsaturated fatty acids have promising cancer-preventive effects when introduced early in life, and warrant further research to elucidate the mechanisms of action.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.