ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2011
Tetrofosmin early time gated post-stress single-photon emission computed tomography imaging: feasibility and potential benefits.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficiency of tetrofosmin versus sestamibi achieved through shorter injection-to-imaging times: A systematic review of the literature.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- Detection of post-exercise stunning by early gated SPECT myocardial perfusion imaging: results from the IAEA multi-center study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Trial
- Accurate and efficient rapid acquisition early post-injection stress-first CZT SPECT myocardial perfusion imaging with tetrofosmin and attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Fast myocardial perfusion imaging withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Myocardial perfusion imaging with 99mTc-labeled radiopharmaceuticals: How fast can a stress-rest same-day imaging protocol be completed?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Should early post-stress imaging be performed on a routine clinical basis for myocardial perfusion studies?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Should HIV-infected patients be screened for silent myocardial ischaemia using gated myocardial perfusion SPECT?European journal of nuclear medicine and molecular imaging · 2013Article
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8 authors.
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Abstract
backgroundThe purpose of this study is to evaluate the feasibility, the image quality, and the clinical relevance of an early gated post-stress (GPS) single-photon emission computed tomography (SPECT) tetrofosmin (Myoview™-GE Healthcare) acquisition protocol. Time delay between myocardial technetium-labeled tracer administration and SPECT acquisition is usually about 30 minutes after stress, and 45 to 60 minutes at rest: because of the absence of significant redistribution, perfusion images are related to stress even 30 minutes after stress injection, while function and thickening data obtained with gated acquisition 30 minutes after stress are mainly related to rest conditions.
methods194 patients were prospectively included and analyzed, in a multicenter registry. Three gated-SPECT 99(m)Tc-Tetrofosmin studies were performed per patient: GPS-SPECT, 30 minutes post-stress (GS30), and at rest (GR30).
resultsGPS image quality was excellent/good (93.9%), and similar to GS30 images (96.6%). The presence of adjacent myocardial sub-diaphragmatic activity on GPS images was similar to GS30 images (24% vs 22%), and less frequent than on GR30 images (31%). For perfusion, thickening, and motion scores, there was no significant difference between early and 30 minute post-stress in the global patient population, but significant differences were observed between GPS and GS30 for LVEF (65% ± 15% vs 63% ± 14%). In the ischemic patients, with the stress-rest protocol, the perfusion score was 14.2 on GPS images and 12.4 on GS30 images (P = .002).
conclusionsTetrofosmin early GPS-SPECT is feasible without impairment of image quality (better count rate). Ischemic defect size on early post-stress images is slightly more pronounced than at 30 minutes: this could modify therapeutic decision. This technique produces reliable function information during early post-stress period, and might be useful for disclosing transient motion abnormalities.
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