Evidence map›Paper›PMID 21063896›Full record

ArticleJournal of neuro-oncology2011

Primary intracranial leiomyosarcoma in an immunocompetent patient: case report.

Yasunori Fujimoto, Junko Hirato, Akatsuki Wakayama, Toshiki Yoshimine

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neuro-oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yasunori FujimotoDepartment of Neurosurgery, Osaka Neurological Institute, 2-6-23 Shonai Takara-Machi, Toyonaka, Osaka 561-0836, Japan. yfujimoto@nsurg.med.osaka-u.ac.jp
Junko Hirato
Akatsuki Wakayama
Toshiki Yoshimine
Osaka Neurological Institute · JPGunma University Hospital · JPOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of intracranial leiomyosarcoma (LMS) arising after resection of neurofibroma at the cerebellopontine angle. A 45-year-old immunocompetent woman presented with recurrence of a tumor 9 years after resection performed in another hospital. Magnetic resonance imaging demonstrated a heterogeneously enhancing, dura-based mass at the left cerebellopontine angle. The tumor was subtotally removed via lateral suboccipital craniotomy. LMS was diagnosed based on histological and immunohistochemical findings. Postoperatively, although the patient was treated using local radiotherapy, she died due to rapid regrowth of the tumor. Reevaluation of the specimen obtained in the first operation led to a diagnosis of neurofibroma. Both LMS and neurofibroma rarely occur intracranially. LMS is generally thought to arise from smooth muscle cells of the blood vessels or pluripotent mesenchymal cells. In this case, LMS might also have originated from smooth muscle cells of the vessels in the neurofibroma, possibly associated with mechanical and/or heat stimulation during the previous surgery.

Indexed as

Brain NeoplasmsImmunocompetenceLeiomyosarcomaActinsCalmodulin-Binding ProteinsDesminFemaleGadoliniumHumansKi-67 AntigenMagnetic Resonance ImagingMiddle AgedS100 ProteinsTubulinACTA2 protein, humanActinsCalmodulin-Binding ProteinsDesminGadoliniumKi-67 AntigenS100 ProteinsTUBB3 protein, humanTubulin

Identifiers

PMID21063896
OpenAlexW1990084453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.