Evidence map›Paper›PMID 21063868›Full record

Trial reportPsychopharmacology2011

Positive effects of Red Bull® Energy Drink on driving performance during prolonged driving.

Monique A J Mets, Sander Ketzer, Camilla Blom, Maartje H van Gerven, Gitta M van Willigenburg, Berend Olivier, Joris C Verster

2 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01007877 nacompletednot on this map

'Study to Investigate the Effects of an Energy Drink During a 15-minute Break Versus Continued Driving on Driving Performance in the STISIM Driving Simulator'

TypeinterventionalSponsorUtrecht Institute for Pharmaceutical SciencesRan2009 to 2010Enrolled24ConditionsDriver SleepinessArmsRed Bull Energy drink
NCT07588022 narecruitingnot on this mapstarted 2026, after this paper: background citation

Acute Effects of an Explosive Cocktail With Energy Drinks That is Trendy Among Young People, the Jägerbomb

TypeinterventionalSponsorFundació Institut Germans Trias i PujolRan2026 to 2027Enrolled24ConditionsAlcohol Drinking, Healthy Adult Participants, Binge Alcohol Consumption, Energy DrinksArmsJägermeister and Energy Drink (Jägerbomb), Jägermeister and Energy Drink Placebo, Alcohol Placebo and Energy Drink Placebo
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 69 citations in OpenAlex.

  1. Effects of Mixing Energy Drinks With Alcohol on Driving-Related Skills.The international journal of neuropsychopharmacology · 2022
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  14. Sleep disorders as a cause of motor vehicle collisions.International journal of preventive medicine · 2013
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  15. Energy drinks mixed with alcohol: misconceptions, myths, and facts.International journal of general medicine · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Monique A J MetsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, P.O. Box 80082, 3508 TB, Utrecht, The Netherlands.
Sander Ketzer
Camilla Blom
Maartje H van Gerven
Gitta M van Willigenburg
Berend Olivier
Joris C Verster
Utrecht University · NLPharmo Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to examine if Red Bull® Energy Drink can counteract sleepiness and driving impairment during prolonged driving.

methodsTwenty-four healthy volunteers participated in this double-blind placebo-controlled crossover study. After 2 h of highway driving in the STISIM driving simulator, subjects had a 15-min break and consumed Red Bull® Energy Drink (250 ml) or placebo (Red Bull® Energy Drink without the functional ingredients: caffeine, taurine, glucuronolactone, B vitamins (niacin, pantothenic acid, B6, B12), and inositol) before driving for two additional hours. A third condition comprised 4 h of uninterrupted driving. Primary parameter was the standard deviation of lateral position (SDLP), i.e., the weaving of the car. Secondary parameters included SD speed, subjective driving quality, sleepiness, and mental effort to perform the test.

resultsNo significant differences were observed during the first 2 h of driving. Red Bull® Energy Drink significantly improved driving relative to placebo: SDLP was significantly reduced during the 3rd (p < 0.046) and 4th hour of driving (p < 0.011). Red Bull® Energy Drink significantly reduced the standard deviation of speed (p < 0.004), improved subjective driving quality (p < 0.0001), and reduced mental effort to perform the test (p < 0.024) during the 3rd hour of driving. Subjective sleepiness was significantly decreased during both the 3rd and 4th hour of driving after Red Bull® Energy Drink (p < 0.001 and p < 0.009, respectively). Relative to uninterrupted driving, Red Bull® Energy Drink significantly improved each parameter.

conclusionRed Bull® Energy Drink significantly improves driving performance and reduces driver sleepiness during prolonged highway driving.

Indexed as

Automobile DrivingBeveragesAdultAnalysis of VarianceAutomobile Driver ExaminationCaffeineCentral Nervous System StimulantsCross-Over StudiesDouble-Blind MethodEnergy MetabolismFatigueFatigue Syndrome, ChronicFemaleHumansMaleMotor SkillsCaffeineCentral Nervous System Stimulants

Identifiers

PMID21063868
PMCPMC3053448
OpenAlexW2092144252

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.