SynthesisJournal of general internal medicine2011
The diagnostic performance of multi-slice coronary computed tomographic angiography: a systematic review.
Synthesis in Journal of general internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of prospectively gated, 128-slice or greater CTCA at high heart rates: a systematic review and meta-analysis.Journal of medical radiation sciences · 2021Pooled it
- CT Angiography Followed by Invasive Angiography in Patients With Moderate or Severe Ischemia-Insights From the ISCHEMIA Trial.JACC. Cardiovascular imaging · 2021Trial
- Radiological outpatient' visits to avoid inappropriate cardiac CT examinations: an 8-year experience report.La Radiologia medica · 2021Observational
- Risk factors and utility of maximum carotid intima-media thickness as a surrogate marker for coronary artery stenosis.Therapeutics and clinical risk management · 2018Article
- Incidental extra-cardiac findings onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Static and dynamic assessment of myocardial perfusion by computed tomography.European heart journal. Cardiovascular Imaging · 2016Review
- Superior CT coronary angiography image quality at lower radiation exposure with second generation 320-detector row CT in patients with elevated heart rate: a comparison with first generation 320-detector row CT.Cardiovascular diagnosis and therapy · 2014Article
- Cost-effectiveness of different diagnostic strategies in suspected stable coronary artery disease in Portugal.Arquivos brasileiros de cardiologia · 2014Article
- Downstream testing and subsequent procedures after coronary computed tomographic angiography following coronary stenting in patients ≥65 years of age.The American journal of cardiology · 2012Article
- Toward evidence-based decisions in diagnostic radiology: a research and rating process for multiple decision-makers.Academic radiology · 2012Article
- The role of coronary CT in the assessment and diagnosis of patients with chest pain.Clinical medicine (London, England) · 2012Article
- Diagnostic performance of multislice CCTA: is it ready for clinical use?Journal of general internal medicine · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of coronary computed tomographic angiography (CCTA) for evaluation of patients with suspected coronary artery disease (CAD) is growing rapidly, yet questions remain regarding its diagnostic accuracy and its impact on clinical decision-making and patient outcomes.
methodsA systematic literature review was conducted to identify studies examining (a) CCTA's diagnostic accuracy; and (b) the impact of CCTA on clinical decision-making and/or patient outcomes. Diagnostic accuracy estimates were limited to patient-based analyses of occlusion; outcome studies were eligible for inclusion if they involved patients at low-to-intermediate risk of CAD. Pooled accuracy estimates were derived using bivariate random effects models; non-diagnostic CCTA results were conservatively assumed to be false positives.
resultsA total of 42 diagnostic accuracy studies and 11 patient outcome studies were identified. The pooled mean sensitivity for CCTA in primary analyses was 98% (95% CI: 96%, 99%); specificity was 85% (81%, 89%). A small number of outcome studies set primarily in the emergency department found triage of low-risk patients using CCTA produced no serious adverse outcomes and was time-saving relative to standard triage care. Outcome studies in the outpatient setting were limited to four case series that did not directly compare patient care or outcomes with those of contemporaneous patients evaluated without CCTA.
conclusionsCCTA appears to have high diagnostic accuracy in patients with suspected CAD, but its potential impact on clinical decision-making and patient outcomes is less well-understood, particularly in non-emergent settings.
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