Evidence map›Paper›PMID 21062906›Full record

ReviewClinical chemistry2011

Prediabetes as a therapeutic target.

Omid Rad Pour, Samuel Dagogo-Jack

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Prediabetes as a toxic environment for the initiation of microvascular and macrovascular complications.Experimental biology and medicine (Maywood, N.J.) · 2016 · on this map
    Review
  11. Article
  12. Article
  13. Article
  14. Serum uric acid level and its association with cardiometabolic risk factors in prediabetic subjects.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Omid Rad PourDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Samuel Dagogo-Jack
University of Tennessee Health Science Center · US

Funding

USE OF MOTIVATIONAL INTERVIEWING TO MANAGE TYPE I DIABETESM01RR000211 · NCRR · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KITABCHI, ABBAS E. · 1985 to 2006
$9.6M
Post-DPP Followup StudiesU01DK048411 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI DAGOGO-JACK, M.D., D.SC., SAMUEL · 1994 to 2022
$9.2M
Pathobiology of Prediabetes in A Bi-Racial CohortR01DK067269 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI DAGOGO-JACK, M.D., D.SC., SAMUEL · 2006 to 2017
$6.1M
NCRR NIH HHS M01 RR000211NCRR NIH HHS M01 RR00211NIDDK NIH HHS R01 DK067269NIDDK NIH HHS U01 DK048411
6 · The paper itself

Abstract

backgroundThe term "prediabetes" is used to describe a condition that involves impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). IGT is defined by a 2-h oral glucose tolerance test plasma glucose concentration >140 mg/dL (7.8 mmol/L) but <200 mg/dL (11.1 mmol/L), and IFG is defined by a fasting plasma glucose concentration ≥100 mg/dL (5.6 mmol/L), but <126 mg/dL (7.0 mmol/L). Studies have shown that people with prediabetes tend to develop type 2 diabetes within 10 years and are at increased risk for cardiovascular disease and death even before the development of diabetes. CONTENT: In this minireview we discusses the epidemiology, pathophysiology, and clinical implications of prediabetes. The rationale for therapeutic intervention in people with prediabetes, the goals of intervention, and the specific tools for intervention are presented. Emphasis is placed on data from randomized controlled clinical trials, whenever such data are available. SUMMARY: Approximately 57 million Americans have prediabetes and are consequently at risk for cardiometabolic complications. Lifestyle modifications (dietary restriction and exercise) and certain medications can prevent the development of diabetes in persons with prediabetes. Lifestyle intervention also has been demonstrated to decrease cardiovascular disease risk markers, although data on clinical events are lacking.

Indexed as

Cardiovascular DiseasesDiabetes MellitusHumansHypoglycemic AgentsLife StylePractice Guidelines as TopicPrediabetic StateHypoglycemic Agents

Identifiers

PMID21062906
PMCPMC4395135
OpenAlexW2106405861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.