Evidence map›Paper›PMID 21061860›Full record

SynthesisSleep2010

Continuous positive airway pressure reduces risk of motor vehicle crash among drivers with obstructive sleep apnea: systematic review and meta-analysis.

Stephen Tregear, James Reston, Karen Schoelles, Barbara Phillips

Registry-linked trialOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Sleep, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03345524 (Predictive Analytics and Peer-Driven Intervention for Guideline-based Care for Sleep Apnea), which is not on this map. Cited by 120 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 6 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03345524 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Predictive Analytics and Peer-Driven Intervention for Guideline-based Care for Sleep Apnea

TypeinterventionalSponsorUniversity of ArizonaRan2017 to 2018Enrolled145ConditionsObstructive Sleep ApneaArmsPeer-Buddy System, Usual Care
3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 6 syntheses or guidelines pooled it, 321 citations in OpenAlex.

  1. Patient-reported outcomes with hypoglossal nerve stimulation for treatment of obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Pooled it
  2. Pooled it
  3. European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2021
    Guideline
  4. Management of Obstructive Sleep Apnea in Commercial Motor Vehicle Operators: Recommendations of the AASM Sleep and Transportation Safety Awareness Task Force.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017
    Guideline
  5. Pooled it
  6. Guideline
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Effects of armodafinil on simulated driving and self-report measures in obstructive sleep apnea patients prior to treatment with continuous positive airway pressure.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2013
    Trial
  12. Article
  13. Review
  14. Impact of Philips device recall on adults with obstructive sleep apnea treated with PAP therapy: Results of a cross-national patient survey.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Stephen TregearMANILA Consulting Group, McLean, VA, USA.
James Reston
Karen Schoelles
Barbara Phillips
ECRI Institute · USSleepMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextObstructive sleep apnea (OSA) is associated with an increased risk of motor vehicle crash.

objectiveWe performed a systematic review of the literature concerning the impact of continuous positive airway pressure (CPAP) treatment on motor vehicle crash risk among drivers with OSA. The primary objective was to determine whether CPAP use could reduce the risk of motor vehicle crash among drivers with OSA. A secondary objective involved determining the time on treatment required for CPAP to improve driver safety. DATA SOURCES: We searched seven electronic databases (MEDLINE, PubMed (PreMEDLINE), EMBASE, PsycINFO, CINAHL, TRIS, and the Cochrane library) and the reference lists of all obtained articles. STUDY SELECTION: We included studies (before-after, case-control, or cohort) that addressed the stated objectives. We evaluated the quality of each study and the interplay between the quality, quantity, robustness, and consistency of the evidence. We also tested for publication bias. DATA EXTRACTION: Data were extracted by two independent analysts. When appropriate, data were combined in a fixed or random effects meta-analysis.

resultsA meta-analysis of 9 observational studies examining crash risk of drivers with OSA pre- vs. post-CPAP found a significant risk reduction following treatment (risk ratio = 0.278, 95% CI: 0.22 to 0.35; P < 0.001). Although crash data are not available to assess the time course of change, daytime sleepiness improves significantly following a single night of treatment, and simulated driving performance improves significantly within 2 to 7 days of CPAP treatment.

conclusionsObservational studies indicate that CPAP reduces motor vehicle crash risk among drivers with OSA.

Indexed as

Accidents, TrafficContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedOdds RatioRisk FactorsSleep Apnea, ObstructiveTime Factors

Identifiers

PMID21061860
PMCPMC2941424
OpenAlexW55607816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.