Trial reportEuropean journal of nuclear medicine and molecular imaging2011
Prognostic implications of post-stress ejection fraction decrease detected by gated SPECT in the absence of stress-induced perfusion abnormalities.
Trial report in European journal of nuclear medicine and molecular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Detection of post-exercise stunning by early gated SPECT myocardial perfusion imaging: results from the IAEA multi-center study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Trial
- Patient centric performance and interpretation of SPECT and SPECT/CT myocardial perfusion imaging: a clinical consensus statement of the European Association of Cardiovascular Imaging of the ESC.European heart journal. Imaging methods and practice · 2025Review
- Implications of transient ischemic dilatation and impaired left ventricular ejection fraction reserve in patients with normal stress myocardial perfusion imaging and elevated coronary artery calcium.The international journal of cardiovascular imaging · 2022Article
- Prognostic significance of post-stress reduction in left ventricular ejection fraction with adenosine stress in Jordanian patients with normal myocardial perfusion.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Do we really need to look at volumetric measurements withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Impact of imaging protocol on left ventricular ejection fraction using gated-SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Clinical value of hyperemic left ventricular systolic function in vasodilator stress testing.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Review
- Myocardial blood flow and left ventricular functional reserve in hypertrophic cardiomyopathy: aEuropean journal of nuclear medicine and molecular imaging · 2017Article
- Warranty periods for normal myocardial perfusion stress SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Article
- Utility of reprojected tomograms.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Prediction of all-cause mortality from gated-SPECT global myocardial wall thickening: comparison with ejection fraction and global longitudinal 2D-strain.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- The relationship between ischemia-induced left ventricular dysfunction, coronary flow reserve, and coronary steal on regadenoson stress-gated (82)Rb PET myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Post-stress left ventricular ejection fraction drop in patients with diabetes: a gated myocardial perfusion imaging study.BMC cardiovascular disorders · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe prognostic meaning of a post-stress ejection fraction (EF) decrease detected by perfusion gated SPECT is still unclear.We therefore followed up patients with post-stress EF decrease in the absence of stress-induced perfusion abnormalities.
methodsWe prospectively enrolled 57 consecutive patients with post-stress EF drop ≥ 5 EF units and summed difference score (SDS) ≤ 1. They were followed up for more than 1 year and their outcome was compared with a group of sex- and age-matched controls with the same SDS but without EF decrease.
resultsDuring follow-up there were 13 events (1 cardiac death, 1 non-fatal myocardial infarction, 1 congestive heart failure and 10 late revascularizations). In the control group we registered six events. There was a significant difference (p<0.0001) between the event-free survival curves of the two groups.
conclusionThe event rate of patients with post-stress EF decrease ≥ 5 EF units is relatively high and is significantly worse than that of a control group of patients with similarly normal SDS but without EF changes. Therefore, a post-stress EF decrease without stress-induced perfusion abnormalities should be cautiously interpreted.
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