Evidence map›Paper›PMID 21058664›Full record

ArticleEnvironmental science & technology2010

Label-free chemiresistive immunosensors for viruses.

Dhammanand J Shirale, Mangesh A Bangar, Miso Park, Marylynn V Yates, Wilfred Chen, Nosang V Myung, Ashok Mulchandani

Abstract read
In one paragraph

Article in Environmental science & technology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Label-free detection and manipulation of single biological nanoparticles.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2016
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dhammanand J ShiraleDepartment of Chemical and Environmental Engineering, University of California, Riverside, California 92521, United States.
Mangesh A Bangar
Miso Park
Marylynn V Yates
Wilfred Chen
Nosang V Myung
Ashok Mulchandani

Funding

Wearable Nanosensor Array for Real-Time Monitoring of Diesel and Gasoline ExhaustU01ES016026 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI MULCHANDANI, ASHOK · 2007 to 2010
$2.7M
NIEHS NIH HHS U01 ES016026NIEHS NIH HHS U01ES016026
6 · The paper itself

Abstract

We report development, characterization, and testing of chemiresistive immunosensors based on single polypyrrole (Ppy) nanowire for highly sensitive, specific, label free, and direct detection of viruses. Bacteriophages T7 and MS2 were used as safe models for viruses for demonstration. Ppy nanowires were electrochemically polymerized into alumina template, and single nanowire based devices were assembled on a pair of gold electrodes by ac dielectrophoretic alignment and anchored using maskless electrodeposition. Anti-T7 or anti-MS2 antibodies were immobilized on single Ppy nanowire using EDC-NHS chemistry to fabricate nanobiosensor for the detection of corresponding bacteriophage. The biosensors showed excellent sensitivity with a lower detection limit of 10(-3) plaque forming unit (PFU) in 10 mM phosphate buffer, wide dynamic range and excellent selectivity. The immunosensors were successfully applied for the detection of phages in spiked untreated urban runoff water samples. The results show the potential of these sensors in health care, environmental monitoring, food safety and homeland security for sensitive, specific, rapid, and affordable detection of bioagents/pathogens.

Indexed as

Aluminum OxideBacteriophage T7Biosensing TechniquesElectrochemical TechniquesElectrodesEnvironmental MonitoringImmunologic TechniquesLevivirusModels, BiologicalNanowiresPolymersPyrrolesVirusesWater MicrobiologyWater PollutantsAluminum OxidePolymerspolypyrrolePyrrolesWater Pollutants

Identifiers

PMID21058664
PMCPMC3292280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.